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Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence
Cigarette smoking is a leading cause of preventable mortality worldwide. Nicotine dependence, which reduces the likelihood of quitting smoking, is a heritable trait with firmly established associations with se...
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Article
Open AccessGenome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence
We conducted a 1000 Genomes–imputed genome-wide association study (GWAS) meta-analysis for nicotine dependence, defined by the Fagerström Test for Nicotine Dependence in 17 074 ever smokers from five European-...