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Open AccessOlfactory receptor Olfr78 (prostate-specific G protein-coupled receptor PSGR) expression in arterioles supplying skeletal and cardiac muscles and in arterioles feeding some murine organs
The olfactory receptor Olfr78 (prostate-specific G protein-coupled receptor PSGR) is a member of the G protein-coupled receptor family mediating olfactory chemosensation, but it is additionally expressed in ot...
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Article
Open AccessGlucocorticoids dexamethasone and prednisolone suppress fibroblast growth factor 23 (FGF23)
Fibroblast growth factor 23 (FGF23) is a hormone mainly secreted by bone cells. Its most prominent effects are the regulation of renal phosphate reabsorption and calcitriol (active vitamin D, 1,25(OH)2D3) formati...
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Chapter
Odorant Sensing
Chemosensory perception is one of the most important systems for appraisal of the environment. In contrast to physical sensory modalities, whose stimuli nature is constant (light, sound), the ever-changing odo...
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Article
Open AccessDecreased demand for olfactory periglomerular cells impacts on neural precursor cell viability in the rostral migratory stream
The subventricular zone (SVZ) provides a constant supply of new neurons to the olfactory bulb (OB). Different studies have investigated the role of olfactory sensory input to neural precursor cell (NPC) turnov...
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Article
Open AccessOlfactory discrimination largely persists in mice with defects in odorant receptor expression and axon guidance
The defining feature of the main olfactory system in mice is that each olfactory sensory neuron expresses only one of more than a thousand different odorant receptor genes. Axons expressing the same odorant re...
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Article
Untypical connectivity from olfactory sensory neurons expressing OR37 into higher brain centers visualized by genetic tracing
The OR37 subfamily of odorant receptors (ORs) exists exclusively in mammals. In contrast to ORs in general, they are highly conserved within and across species. These unique features raise the question, whethe...
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Article
Internalization of odorant-binding proteins into the mouse olfactory epithelium
The detection of odorants in vertebrates is mediated by chemosensory neurons that reside in the olfactory epithelium of the nose. In land-living species, the hydrophobic odorous compounds inhaled by the airstr...
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Reference Work Entry In depth
Transduction in Olfactory System
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Article
Fachspezifische Aufgabe und organspezifische Therapie beim Morbus Fabry
Der Morbus Fabry ist eine seltene genetische Erkrankung, bei der es zu einer progressiven Speicherung von Sphingolipiden (Globotriaosylceramid) in den Lysosomen aller Körperzellen kommt. Die Einlagerungen find...
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Alkohol und Herz-Kreislauf
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Article
Projection pattern of nerve fibers from the septal organ: DiI-tracing studies with transgenic OMP mice
The septal organ represents one of the three chemosensory subsystems found in most vertebrate species. Analyzing the projection pattern of septal organ neurons using the OMP-GFP transgenic mouse line revealed ...
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Article
Extraepithelial cells expressing distinct olfactory receptors are associated with axons of sensory cells with the same receptor type
During critical phases of mouse development, axons from olfactory sensory neurons grow out of the nasal neuroepithelium and navigate through the connective mesenchyme tissue towards their targets in the devel...
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Chapter
A Unique Subfamily of Olfactory Receptors
The sense of smell allows terrestrial animals to respond to an immense variety of odorant molecules. The discriminatory capacity of this sense is derived from precise information processing at different levels...
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Chapter
Alkohol und Herz-Kreislauf
Alkoholkonsum und Alkoholfolgekrankheiten spielen in Industrieländern eine bedeutende Rolle. Im Bereich der kardiovaskulären Erkrankungen muß man zwischen möglichen positiven Effekten von Alkohol auf die kardi...
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Article
Decline and recovery of olfactory receptor expression following unilateral bulbectomy
The effects of unilateral olfactory bulb ablation upon the odorant receptor expression were studied during the degeneration/regeneration process in the olfactory epithelium of adult rats. Using the in situ hy...
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Article
Laminar segregation of odorant receptor expression in the olfactory epithelium
The laminar segregation of sensory neurons expressing a distinct receptor type was determined in tissue sections through the olfactory epithelium by in situ hybridization employing receptor-specific probes. Re...
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Article
Molecular genetics of mammalian olfaction
Olfaction plays a crucial role in the survival of most animal species; it is remarkable in its ability to recognize and discriminate numerous airborne molecules, yet is one of the least understood senses. The ...
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Article
Generation of monoclonal antibodies detecting specific epitopes in olfactory and respiratory epithelia
Two panels of monoclonal antibodies have been generated, each panel having a distinct specificity for antigens located in the ciliary zone of either the olfactory or respiratory epithelium of rats. Tissue spec...
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Article
Jungvögel sterben im harten Winter zuerst: Winterverluste beim Austernfischer,Haematopus ostralegus
Nach einer 30tägigen Frostperiode im Februar/März 1986 konnten auf der niederländischen Wattenmeerinsel Texel 86 tote Austernfischer untersucht werden. 67% aller Totfunde wiesen Deformationen an Schnäbeln und ...
