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Article
Open AccessChanges in prostate cancer survival among insured patients in relation to USPSTF screening recommendations
To investigate the effects of the U.S. Preventive Services Task Force’s (USPSTF) 2012 recommendation against prostate-specific antigen (PSA)-based screening for prostate cancer on survival disparities based on...
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Article
Correction to: Unintended consequences of decreased PSA-based prostate cancer screening
In the original publication, part of funding information was missed.
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Article
Open AccessSimilar incidence of DNA damage response pathway alterations between clinically localized and metastatic prostate cancer
In this era of precision medicine, the DNA damage response (DDR) pathway has been shown to be a viable target of intervention in metastatic castration-resistant prostate cancer (CRPC) as approximately one-thir...
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Article
Unintended consequences of decreased PSA-based prostate cancer screening
In May 2012, the US Preventive Services Task Force issued a grade D recommendation against PSA-based prostate cancer screening. Epidemiologists have concerns that an unintended consequence is a problematic inc...
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Article
Open AccessLongitudinal recovery patterns of penile length and the underexplored benefit of long-term phosphodiesterase-5 inhibitor use after radical prostatectomy
Penile length (PL) shortening is an underreported phenomenon following radical prostatectomy (RP) and risk factors are not fully explored. We aimed to describe longitudinal patterns of PL recovery and evaluate...
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Article
Open AccessWNT5A induces castration-resistant prostate cancer via CCL2 and tumour-infiltrating macrophages
Although the standard treatment for the patients with recurrent and metastatic prostate cancer (CaP) is androgen deprivation therapy, castration-resistant prostate cancer (CRPC) eventually emerges. Our previou...
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Reference Work Entry In depth
Transitional Cell Carcinoma
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Article
Open AccessOncologic outcomes in men with metastasis to the prostatic anterior fat pad lymph nodes: a multi-institution international study
The presence of lymph nodes (LN) within the prostatic anterior fat pad (PAFP) has been reported in several recent reports. These PAFP LNs rarely harbor metastatic disease, and the characteristics of patients w...
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Article
Open AccessDecreased selenium-binding protein 1 mRNA expression is associated with poor prognosis in renal cell carcinoma
The anticancer effects of selenium may be mediated by selenium-binding proteins, such as SELENBP1. The association between SELENBP1 expression levels and clinicopathologic parameters was assessed in renal cell...
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Article
Open AccessConcern for overtreatment using the AUA/ASTRO guideline on adjuvant radiotherapy after radical prostatectomy
Recently, three prospective randomized trials have shown that adjuvant radiotherapy (ART) after radical prostatectomy for the patients with pT3 and/or positive margins improves biochemical progression-free sur...
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Living Reference Work Entry In depth
Transitional Cell Carcinoma
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Article
CREBZF, a novel Smad8-binding protein
Smads are the secondary messengers of the transforming growth factor-β (TGF-β) signaling pathway. TGF-β receptors phosphorylate the Receptor Smads (R-Smads) upon ligand binding; activated R-Smads translocate t...
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Article
Impact of Partin nomogram on presurgical planning: intrafascial versus interfascial nerve sparing during robot-assisted radical prostatectomy
We studied the impact of using the Partin nomogram in tailoring the nerve sparing approach during robot-assisted radical prostatectomy. From July 2008 to July 2009, 168 patients underwent robot-assisted radica...
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Article
Open AccessA Four-Gene Signature Predicts Disease Progression in Muscle Invasive Bladder Cancer
There are no reliable criteria to handle disease progression of muscle invasive bladder cancer (MIBC), which strongly influences patient survival. Therefore, an accurate predicting method to identify progressi...
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Reference Work Entry In depth
Transitional Cell Carcinoma
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Article
Early assessment of patient satisfaction and health-related quality of life following robot-assisted radical prostatectomy
Impairments in health-related quality of life (HRQOL) and patient satisfaction after definitive treatment for localized prostate cancer can be significant. We assessed patient satisfaction associated with HRQO...
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Reference Work Entry In depth
Transitional Cell Carcinoma
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Article
Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β superfamily and signal through a number of membrane receptors. We have previously demonstrated that the loss of expression of BMP...
