16 Result(s)
within
Ingrid J. Pickering
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Article
Open AccessWide field imaging energy dispersive X-ray absorption spectroscopy
A new energy dispersive X-ray absorption spectroscopy (EDXAS) method is presented for simultaneous wide-field imaging and transmission X-ray absorption spectroscopy (XAS) to enable rapid imaging and speciation...
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Living Reference Work Entry In depth
X-ray Fluorescence Imaging: Elemental and Chemical Speciation Map** of Biological Systems
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Living Reference Work Entry In depth
X-ray Absorption Spectroscopy of Metals in Biology
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Article
Open AccessPathogenic implications of distinct patterns of iron and zinc in chronic MS lesions
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) in which oligodendrocytes, the CNS cells that stain most robustly for iron and myelin are the targets...
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Reference Work Entry In depth
X-Ray Fluorescence Imaging: Elemental and Chemical Speciation Map** of Biological Systems
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Reference Work Entry In depth
X-Ray Absorption Spectroscopy of Metals in Biology
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Article
The use of field-based mesocosm systems to assess the effects of uranium milling effluent on fathead minnow (Pimephales promelas) reproduction
Northern Saskatchewan, Canada is home to a uranium milling operation that discharges a complex milling effluent containing nutrients, cations and anions, and many metals including selenium (Se). Se has the pot...
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Article
Towards a custom chelator for mercury: evaluation of coordination environments by molecular modeling
A chelator is a molecule which binds a metal or metalloid ion by two or more functional groups to form a stable ring complex known as a chelate. Despite the widespread clinical use of so-called chelation thera...
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Article
Dynamic accumulation and redistribution of methylmercury in the lens of develo** zebrafish embryos and larvae
Neurotoxic methylmercury compounds are widespread in the environment and human exposure worries many communities worldwide. Despite numerous studies addressing methylmercury toxicity, the detailed mechanisms u...
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Article
The chemical forms of mercury in human hair: a study using X-ray absorption spectroscopy
Human hair is frequently used as a bioindicator of mercury exposure. We have used X-ray absorption spectroscopy to examine the chemical forms of mercury in human hair samples taken from individuals with high f...
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Chapter and Conference Paper
X-RAY ABSORPTION SPECTROSCOPY IN BIOLOGY AND CHEMISTRY
X-ray absorption spectroscopy has widespread applications to biology and chemistry. Here we review the principles of the technique and discuss some chemical and biological applications.
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Article
A cadmium enzyme from a marine diatom
The ocean biota contains a vast reservoir of genomic diversity1. Here we present the sequence and preliminary characterization of a protein that is a cadmium-containing carbonic anhydrase from the marine diatom T...
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Article
Open AccessProduction of Se-methylselenocysteine in transgenic plants expressing selenocysteine methyltransferase
It has become increasingly evident that dietary Se plays a significant role in reducing the incidence of lung, colorectal and prostate cancer in humans. Different forms of Se vary in their chemopreventative ef...
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Article
Thioredoxin h overexpressed in barley seeds enhances selenite resistance and uptake during germination and early seedling development
The uptake, distribution and metabolism of selenite were examined in germinating homozygous barley (Hordeum vulgare L.) grain with thioredoxin h overexpressed in starchy endosperm. Results were related to the nul...
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Article
X-ray absorption spectroscopy of Pyrococcus furiosus rubredoxin
X-ray absorption spectroscopy has been used to probe the frozen solution structure of the metal site in Pyrococcus furiosus rubredoxin in the native, iron-containing protein and in zinc- and mercury-substituted ...
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Article
Diffraction anomalous fine structure: A new technique for Probing Local Atomic Environment
Diffraction anomalous fine structure (DAFS) is the fine structure in the intensity of an X-ray diffraction peak in the vicinity of an absorption edge. DAFS is measured by monitoring the intensity of a diffract...
