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Article
Effect of nitro-conjugated linoleic acid on the inflammatory response of murine macrophages activated with lipopolysaccharide derived from Prevotella intermedia
Nitro-conjugated linoleic acid (NO2-CLA) has been observed to manifest salutary signaling responses, including anti-inflammatory and antioxidant properties. Here, the authors have explored the influence and under...
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Article
Nifedipine attenuates alveolar bone destruction and improves trabecular microarchitectures in mice with experimental periodontitis
Studies have shown that nifedipine exerts anti-inflammatory and immunosuppressive actions in addition to being a calcium channel blocker. The present study was performed to explore the influence of nifedipine ...
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Article
Effect of nifedipine, a calcium channel blocker, on the generation of nitric oxide and interleukin-1β by murine macrophages activated by lipopolysaccharide from Prevotella intermedia
Nifedipine, a calcium channel blocker, has been reported to possess anti-inflammatory and immunosuppressive effects. The current study was undertaken to explore the influence of nifedipine on the generation of...
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Article
Effect of oral administration of β-glucans derived from Aureobasidium pullulans SM-2001 in model mice and rat with atopic dermatitis-like phenotypes
In this study, we investigated the anti-atopic dermatitis (AD) activity of β-glucans derived from Aureobasidium pullulans SM-2001 (βGdAP). βGdAP was orally administered to AD animal models such as vasodilation, a...
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Article
Anti-erythema and anti-edema activities of lactic acid bacteria extracts in mice
We examined the anti-inflammatory activities of 10 lactic acid bacteria extracts, obtained by lysozyme treatment. Among ferments of the 10 species, Bifidobacterium lactis showed the highest anti-erythema (73.4%) ...
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Article
The Edible Red Alga Porphyra yezoensis Promotes Neuronal Survival and Cytoarchitecture in Primary Hippocampal Neurons
The edible red alga Porphyra yezoensis is among the most popular marine algae and is of economic and medicinal importance. In the present study, the neurotrophic and neuroprotective activities of the ethanol extr...
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Article
A 2-week repeated-dose oral toxicity test of Polycalcium, a mixed composition of Polycan and calcium lactate-gluconate 1 : 9 (g/g)
A mixed composition of purified β-glucan from Aureobasidium pullulans and calcium lactate-gluconate 1 : 9(g/g) (polycalcium) was administered orally to female and male Sprague-Dawley (SD) rats once per day for 14...
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Article
Fermented sea tangle attenuates oxidative stress in individuals with a high level of γ-glutamyltransferase: A randomized, double-blind, and placebo-controlled clinical study
A randomized, double-blind, placebo-controlled study of fermented sea tangle (FST) was conducted using 48 healthy volunteers with high levels of γ-glutamyltransferase (GGT). Participants (n=48) were divided into ...
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Article
Safety, functionality and stability tests of Ecklonia cava extract for dermal application
Ecklonia cava demonstrated anti-Propionibacterium acnes and anti-inflammatory activity, without any serious toxic effect, at moderate doses in an in vitro study. However, there has been no in viv...
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Article
Open AccessAntimicrobial activities of stearidonic and gamma-linolenic acids from the green seaweed Enteromorpha linza against several oral pathogenic bacteria
We found that the edible green seaweed Enteromorpha linza displayed potent antimicrobial activity against Prevotella intermedia and Porphyromonas gingivalis. To elucidate the active component of E. linza, isolati...
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Article
Simple freezing and thawing protocol for long-term storage of harvested fresh Undaria pinnatifida
The development of a simple and effective long-term storage protocol for harvested fresh Undaria pinnatifida is required to increase the market for U. pinnatifida products. We investigated the quality of U. pinna...
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Article
A brown alga Sargassum fulvellum facilitates neuronal maturation and synaptogenesis
Sargassum fulvellum (Turner) C. Agardh is an edible brown macroalgae having pharmacological importance. In previous reports, we described the screening of marine algae for their neuritogenic acti...
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Selenocysteine tRNA[Ser]Sec Isoacceptors as Central Components in Selenoprotein Biosynthesis in Eukaryotes
In recent years, a variety of experimental results have led to the surprising conclusion that under certain circumstances the UGA termination codon signals the translational insertion of selenocysteine into pr...
