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  1. Article

    Open Access

    Comparison of early visual outcomes after SMILE using VISUMAX 800 and VISUMAX 500 for myopia: a retrospective matched case–control study

    VISUMAX 800 was introduced to improve the patient experience and clinical outcomes of small incision lenticule extraction (SMILE). This was a retrospective, matched, and case–control study (1:2) controlled for...

    Tae Keun Yoo, Dongyoung Kim, Jung Soo Kim, Hee Sun Kim, Ik Hee Ryu in Scientific Reports (2024)

  2. Article

    Open Access

    A feasibility study on the adoption of a generative denoising diffusion model for the synthesis of fundus photographs using a small dataset

    The generative diffusion model has been highlighted as a state-of-the-art artificial intelligence technique for image synthesis. Here, we show that a denoising diffusion probabilistic model (DDPM) can be used ...

    Hong Kyu Kim, Ik Hee Ryu, Joon Yul Choi, Tae Keun Yoo in Discover Applied Sciences (2024)

  3. No Access

    Article

    Association between metformin use and the risk of develo** open-angle glaucoma among patients with diabetes: a retrospective cohort study and meta-analysis

    Recent studies examining the neuroprotective effects of metformin on open-angle glaucoma (OAG) have failed to provide consistent results. In this study, we investigated the association between metformin use an...

    Hong Kyu Kim, Wanhyung Lee, Ik Hee Ryu, ** Kuk Kim in International Ophthalmology (2024)

  4. No Access

    Article

    Deep learning prediction of steep and flat corneal curvature using fundus photography in post-COVID telemedicine era

    Recently, fundus photography (FP) is being increasingly used. Corneal curvature is an essential factor in refractive errors and is associated with several pathological corneal conditions. As FP-based examinati...

    Joon Yul Choi, Hyungsu Kim, ** Kuk Kim in Medical & Biological Engineering & Computi… (2024)

  5. Article

    Open Access

    Development of a generative deep learning model to improve epiretinal membrane detection in fundus photography

    The epiretinal membrane (ERM) is a common retinal disorder characterized by abnormal fibrocellular tissue at the vitreomacular interface. Most patients with ERM are asymptomatic at early stages. Therefore, scr...

    Joon Yul Choi, Ik Hee Ryu, ** Kuk Kim in BMC Medical Informatics and Decision Making (2024)

  6. Article

    Open Access

    Association between cataract and fatty liver diseases from a nationwide cross-sectional study in South Korea

    This study examined the link between fatty liver disease (FLD) and cataracts, as previous research has suggested that FLD may contribute to metabolic syndrome, systemic inflammation, and potentially cataracts....

    Kyoung Hae Kang, Daeun Shin, Ik Hee Ryu, ** Kuk Kim, In Sik Lee in Scientific Reports (2024)

  7. Article

    Open Access

    Deep Transfer Learning for Ethnically Distinct Populations: Prediction of Refractive Error Using Optical Coherence Tomography

    The mismatch between training and testing data distribution causes significant degradation in the deep learning model performance in multi-ethnic scenarios. To reduce the performance differences between ethnic...

    Rishabh Jain, Tae Keun Yoo, Ik Hee Ryu, Joanna Song in Ophthalmology and Therapy (2024)

  8. Article

    Open Access

    Development of an implantable collamer lens sizing model: a retrospective study using ANTERION swept-source optical coherence tomography and a literature review

    Optimal sizing for phakic intraocular lens (EVO-ICL with KS-AquaPort) implantation plays an important role in preventing postoperative complications. We aimed to formulate optimal lens sizing using ocular biom...

    Taein Kim, Su Jeong Kim, Bo Young Lee, Hye ** Cho, Beom Gi Sa in BMC Ophthalmology (2023)

  9. No Access

    Article

    Machine learning predicting myopic regression after corneal refractive surgery using preoperative data and fundus photography

    Myopic regression after surgery is the most common long-term complication of refractive surgery, but it is difficult to identify myopic regression without long-term observation. This study aimed to develop mac...

    Juntae Kim, Ik Hee Ryu, ** Kuk Kim in Graefe's Archive for Clinical and Experime… (2022)

  10. No Access

    Article

    Deep learning for predicting uncorrected refractive error using posterior segment optical coherence tomography images

    This study aimed to evaluate a deep learning model for estimating uncorrected refractive error using posterior segment optical coherence tomography (OCT) images.

    Tae Keun Yoo, Ik Hee Ryu, ** Kuk Kim, In Sik Lee in Eye (2022)

  11. Article

    Open Access

    Clinical outcomes of the immediate reapplication of small-incision lenticule extraction without adjusting the surgical parameters after suction loss

    This study was to analyze the clinical outcomes of immediate reapplication of small-incision lenticule extraction (SMILE) without adjusting the surgical parameters after suction loss and to compare the outcome...

    Byunghoon Chung, Ik Hee Ryu, In Sik Lee, ** Kuk Kim, Tae-im Kim in Scientific Reports (2022)

  12. No Access

    Article

    Oculomics for sarcopenia prediction: a machine learning approach toward predictive, preventive, and personalized medicine

    Sarcopenia is characterized by a gradual loss of skeletal muscle mass and strength with increased adverse outcomes. Recently, large-scale epidemiological studies have demonstrated a relationship between severa...

    Bo Ram Kim, Tae Keun Yoo, Hong Kyu Kim, Ik Hee Ryu, ** Kuk Kim, In Sik Lee in EPMA Journal (2022)

  13. Article

    Open Access

    Application of generative adversarial networks (GAN) for ophthalmology image domains: a survey

    Recent advances in deep learning techniques have led to improved diagnostic abilities in ophthalmology. A generative adversarial network (GAN), which consists of two competing types of deep neural networks, in...

    Aram You, ** Kuk Kim, Ik Hee Ryu, Tae Keun Yoo in Eye and Vision (2022)

  14. Article

    Open Access

    Artificial intelligence-based nomogram for small-incision lenticule extraction

    Small-incision lenticule extraction (SMILE) is a surgical procedure for the refractive correction of myopia and astigmatism, which has been reported as safe and effective. However, over- and under-correction s...

    Seungbin Park, Hannah Kim, Laehyun Kim, **-kuk Kim in BioMedical Engineering OnLine (2021)

  15. Article

    Open Access

    Reduction of corneal epithelial thickness during medical treatment for myopic regression following FS-LASIK

    To evaluate corneal epithelial thickness change during medical treatment for eyes with myopic regression after femtosecond laser-assisted in situ keratomileusis (FS-LASIK).

    Ik-Hee Ryu, Wook Kyum Kim, Myoung Sik Nam, ** Kook Kim, Sun Woong Kim in BMC Ophthalmology (2020)

  16. Article

    Open Access

    Adopting machine learning to automatically identify candidate patients for corneal refractive surgery

    Recently, it has become more important to screen candidates that undergo corneal refractive surgery to prevent complications. Until now, there is still no definitive screening method to confront the possibilit...

    Tae Keun Yoo, Ik Hee Ryu, Geunyoung Lee, Youngnam Kim, ** Kuk Kim in npj Digital Medicine (2019)

  17. No Access

    Article

    Age-related differences in corneal epithelial thickness measurements with anterior segment optical coherence tomography

    To measure corneal epithelial thickness (CET) in healthy adults and to investigate its variation with age by use of anterior segment optical coherence tomography (OCT).

    Bong Jun Kim, Ik-Hee Ryu, Sun Woong Kim in Japanese Journal of Ophthalmology (2016)