-
Article
Anti-inflammatory and anti-arthritic potential of Coagulansin-A: in vitro and in vivo studies
The current work was designed to evaluate the anti-inflammatory and anti-arthritic potential of Coagulansin-A (Coag-A) using mouse macrophages and arthritic mice. In the LPS-induced RAW 264.7 cells, the effect...
-
Article
Open AccessHormetic effects of thiamethoxam on Schizaphis graminum: demographics and feeding behavior
In agroecosystems, insects contend with chemical insecticides often encountered at sublethal concentrations. Insects’ exposure to these mild stresses may induce hormetic effects, which has consequences for man...
-
Article
Anatomical variations in living donors for liver transplantation—prevalence and relationship
Living donor liver transplantation (LDLT) is a widely accepted option to address the lack of a deceased liver program for transplantation. Understanding vascular and biliary anatomy and their variants is cruci...
-
Article
Exploring safety and efficacy of rivaroxaban after living donor liver transplantation: a retrospective study
Thromboembolic complications remain a significant concern in postoperative patients, particularly those who have undergone liver transplantation. Warfarin has been the standard oral anticoagulant. Direct oral ...
-
Article
Impact of sublethal concentrations of flonicamid on key demographic parameters and feeding behavior of Schizaphis graminum
Flonicamid is a novel systemic insecticide that efficiently controls sap-sucking insect pests. However, the impact of sublethal concentrations of flonicamid on key demographic parameters and the feeding behavi...
-
Article
Analysis of diesel hydrocarbon decomposition using efficient indigenous bacterial isolate: Bacterial growth and biodegradation kinetics
Industrialization and urbanization have increased the demand for petroleum hydrocarbons; hence the likelihood of contamination of air, soil, and water bodies increases. The survival and biodegradation capabili...
-
Article
Open AccessComparative evaluation of biomedical and phytochemical applications of zinc nanoparticles by using Fagonia cretica extracts
The use of the green approach for nanoparticle synthesis yielded noticeable concern due to its eco-friendliness, cost-effectiveness, and reduced production of toxic chemicals. The current study was designed to...
-
Article
Open AccessSynthesis, crystal structure, Hirshfeld surface investigation and comparative DFT studies of ethyl 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate
The ethyl 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate (1), a thiazole ester, was synthesized by refluxing 1-(2-nitrobenzylidene)thiosemicarbazide and ethyl bromopyruvate. The compound is characteri...
-
Article
Structural characterization and antileishmanial activity of newly synthesized organo-bismuth(V) carboxylates: experimental and molecular docking studies
In a quest to discover new formulations for the treatment of various parasitic diseases, a series of heteroleptic triorganobismuth(V) biscarboxylates of type [BiR3(O2CR′)2], where R=C6H5 for 1–4 and p-CH3C6H4 for...
-
Article
Cancer Chemopreventive and Cytotoxic Activities of Isowithametelin from Datura innoxia
Datura innoxia Mill., Solanaceae, an underexplored ethnomedicinal plant, has been empirically evaluated in the current study for the isolation of bioactive agents. A crude extract of D. innoxia leaves was subject...
-
Article
Open AccessPreclinical anticancer studies on the ethyl acetate leaf extracts of Datura stramonium and Datura inoxia
Cancer is a horrific disease relentlessly affecting human population round the globe. Genus Datura encompasses numerous species with reported medicinal uses. However, its potential as a source of natural anticanc...
-
Article
Biological and Phytochemicals Properties of Monotheca buxifolia: An Unexplored Medicinal Plant
Medicinal plants play essential role in improving the human health due to the presence of bioactive constituents. Monotheca buxifolia (family Sapotaceae) leaves and fruit ethanol extracts and their fractions were...
-
Article
Synthesis, characterization and in vitro antioxidant assay of 4-(benzylideneamino)-5-pentadecyl-2H-1,2,4-triazol-3(4H)-ones
The present research paper reports a convenient synthesis of novel 4-(benzylideneamino)-5-pentadecyl-2H-1,2,4-triazol-3(4H)-ones and their in vitro antioxidant assay. The synthesized azomethine-triazole hybrids a...
-
Article
Author Correction: Drier Climatic Conditions Increase Withanolide Content of Withania coagulans Enhancing its Inhibitory Potential against Human Prostate Cancer Cells
The original version of this article unfortunately contained a mistake in the image of Figure 1 and in Table 4. The corrected version of the figure and table is shown here.
-
Article
Drier Climatic Conditions Increase Withanolide Content of Withania coagulans Enhancing Its Inhibitory Potential Against Human Prostate Cancer Cells
Prostate cancer is one of the major causes of cancer-related deaths in men and there is a growing interest in identifying natural compounds for its management. We analyzed bioactive withanolides in Withania coagu...
-
Chapter and Conference Paper
Gas Hydrates Potential of Makran Area, Offshore Pakistan
Gas hydrates are part of the unconventional energy resources called the gas clathrates. The present work focused on the assessment of gas hydrates potential of Makran area, Offshore, Pakistan. The presence of ...
-
Article
Correction to: Implication of OPRM1 A118G Polymorphism in Opioids Addicts in Pakistan: In vitro and In silico Analysis
The original version of this article is missing the Acknowledgments section.
-
Article
Open AccessImplication of OPRM1 A118G Polymorphism in Opioids Addicts in Pakistan: In vitro and In silico Analysis
Single nucleotide polymorphism in OPRM1 gene is associated with hedonic and reinforcing consequences of opioids. Risk and protective alleles may vary in different populations. One hundred healthy controls and 100...
-
Article
Open AccessIpomoea batatas L. Lam. ameliorates acute and chronic inflammations by suppressing inflammatory mediators, a comprehensive exploration using in vitro and in vivo models
Ipomoea batatas L. Lam. is a functional food and belongs to family Convolvulaceae. It is used as an antiinflammatory, aphrodisiac, antiasthmatic, anticonvalescent, antitumor, antanemic and antidiabetic agent by l...
-
Article
Correction to: Ecotoxicological assessment of oil-based paint using three-dimensional multi-species bio-testing model: pre- and post-bioremediation analysis
The original publication of this paper contains a mistake.