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Article
Open AccessFAIR in action - a flexible framework to guide FAIRification
The COVID-19 pandemic has highlighted the need for FAIR (Findable, Accessible, Interoperable, and Reusable) data more than any other scientific challenge to date. We developed a flexible, multi-level, domain-a...
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Article
Open AccessThe FAIR Cookbook - the essential resource for and by FAIR doers
The notion that data should be Findable, Accessible, Interoperable and Reusable, according to the FAIR Principles, has become a global norm for good data stewardship and a prerequisite for reproducibility. Now...
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Article
Open AccessEvaluating lubiprostone for effective bowel preparation before colonoscopy
Colon preparation is a fundamental step for performing a successful colonoscopy. We aimed to evaluate the effectiveness of administering lubiprostone (LB) added to a single dose of oral polyethylene glycol (PE...
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Article
Open AccessPlatformTM, a standards-based data custodianship platform for translational medicine research
Biomedical informatics has traditionally adopted a linear view of the informatics process (collect, store and analyse) in translational medicine (TM) studies; focusing primarily on the challenges in data integ...
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Article
Open AccessHigh dimensional biological data retrieval optimization with NoSQL technology
High-throughput transcriptomic data generated by microarray experiments is the most abundant and frequently stored kind of data currently used in translational medicine studies. Although microarray data is sup...
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Article
Open AccessOptimising parallel R correlation matrix calculations on gene expression data using MapReduce
High-throughput molecular profiling data has been used to improve clinical decision making by stratifying subjects based on their molecular profiles. Unsupervised clustering algorithms can be used for stratifi...
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Chapter and Conference Paper
DSIMBench: A Benchmark for Microarray Data Using R
Parallel computing in R has been widely used to analyse microarray data. We have seen various applications using various data distribution and calculation approaches. Newer data storage systems, such as MySQL ...
