Skip to main content

4 Result(s)

within I. Gonzalez Remove this filter Biomedicine, general Remove this filter

and

  1. No Access

    Article

    Interethnic differences in the relevance of CYP2C9 genotype and environmental factors for diclofenac metabolism in Hispanics from Cuba and Spain

    The aims of this study were to evaluate the diclofenac metabolism in Hispanics from Cuba and Spain and its relation to ethnicity, CYP2C9 genotypes and environmental factors. Diclofenac hydroxylation capacity (con...

    A Llerena, M Alvarez, P Dorado, I González, E Peñas-LLedó… in The Pharmacogenomics Journal (2014)

  2. No Access

    Article

    CYP2D6 genotype and debrisoquine hydroxylation phenotype in Cubans and Nicaraguans

    CYP2D6 genotype and debrisoquine metabolic ratio (MR) were analyzed in 133 Nicaraguan Mestizos (NMs) and 260 Cubans divided into Cuban Mestizos (CMs) and White Cubans (WCs). The frequencies of poor metabolizers (...

    A LLerena, P Dorado, R Ramírez, I González, M Álvarez… in The Pharmacogenomics Journal (2012)

  3. No Access

    Article

    Towards the molecular characterization of the stable producer phenotype of recombinant antibody-producing NS0 myeloma cells

    The loss of heterologous protein expression is one of the major problems faced by industrial cell line developers and has been reported by several authors. Therefore, the understanding of the mechanisms involv...

    Y. Prieto, L. Rojas, L. Hinojosa, I. González, D. Aguiar, K. de la Luz… in Cytotechnology (2011)

  4. Article

    Open Access

    Intron splice acceptor site polymorphism in the hMSH2 gene in sporadic and familial colorectal cancer

    A polymorphism in hMSH2 gene has been associated with an increased susceptibility to develop colorectal cancer (CRC). Here we show that it is a genetic risk factor for CRC in the Spanish population. However, its ...

    M Palicio, I Blanco, S Tórtola, I González, E Marcuello… in British Journal of Cancer (2000)

    Download PDF (216 KB)