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Article
Open AccessMetabolic profile in endothelial cells of chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension
Chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH) are two forms of pulmonary hypertension (PH) characterized by obstructive vasculopathy. Endothelial dysfunction a...
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Chapter
Network and Storage
Natural gas is considered by many to be the most important energy source for the future. The objectives of energy commodities strategic problems can be mainly related to natural gas and deal with the definitio...
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Article
Three-dimensional regional bi-ventricular shape remodeling is associated with exercise capacity in endurance athletes
Endurance athletes develop cardiac remodeling to cope with increased cardiac output during exercise. This remodeling is both anatomical and functional and shows large interindividual variability. In this study...
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Chapter and Conference Paper
The Apulian Territory and the Typical Local Farmhouses: A Case of Study Through Landscape Analysis
The Apulian territory is strongly characterized by a rural architectural heritage with many historical features. Rural and agro-industrial buildings, their reuse or degradation, are the testimony of a history ...
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Chapter and Conference Paper
Modelling of the Thermal Effect of Green Façades on Building Surface Temperature in Mediterranean Climate
Urban Green Infrastructures (UGIs) improve the supply of urban ecosystem services. UGIs can provide benefits such as better urban climate conditions and lower temperature of urban air. They can also limit the ...
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Article
Open AccessStem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
Inhibitors of the mechanistic target of rapamycin (mTOR) are currently used to treat advanced metastatic breast cancer. However, whether an aggressive phenotype is sustained through adaptation or resistance to...
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Article
Kinetic study of the thermal and thermo-oxidative degradations of polylactide-modified films for food packaging
In this study, the thermal degradations of some commercial polylactide (PLA) films, pure and subjected to various superficial treatments, were investigated in both inert (flowing nitrogen) and oxidative (stati...
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Article
Thermal and thermo-oxidative degradations of poly(2,6-dimethyl-1,4-phenylene oxide) (PPO)/copoly(aryl ether sulfone) P(ESES-co-EES) block copolymers: a kinetic study
The thermal degradation of a series of three novel ABA block copolymers of different molar mass (M n), were the block A is a poly(2,6-dimethyl-1,4-phenylene oxide) (PPO), while the block B is a ra...
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Article
Open AccessLymphoma risk in systemic lupus: effects of treatment versus disease activity
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Article
Hepta isobutyl polyhedral oligomeric silsesquioxanes (hib-POSS)
Six polyhedral oligomeric silsesquioxanes (POSSs) with general formula R7 R′1 (SiO1.5)8, where R- was an isobutyl group and R′- a variously substituted phenyl group, namely hepta isobutyl polyhedral oligomeric si...
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Article
Effects of novel reactive toughening agent on thermal stability of epoxy resin
A reactive amino-ended toughener was blended with different commercial epoxy resins namely, diglycidyl ether of bisphenol A, diglycidyl ether of bisphenol F, diglycidyl p-aminophenol and 1,5-naphthalenediamine as...
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Article
Thermal degradation of differently substituted Cyclopentyl Polyhedral Oligomeric Silsesquioxane (CP-POSS) nanoparticles
Seven variously substituted derivatives of polyhedral oligomeric silsesquioxanes (POSSs) with general formula R7R′1 (SiO1.5)8, where R- and R′- were a cyclopentyl and a substituted phenyl group, respectively, wer...
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Article
Germline ATM mutational analysis in BRCA1/BRCA2 negative hereditary breast cancer families by MALDI-TOF mass spectrometry
Biallelic inactivation of ATM gene causes the rare autosomal recessive disorder Ataxia-telangiectasia (A-T). Female relatives of A-T patients have a two-fold higher risk of develo** breast cancer (BC) compared ...
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Article
Open AccessA large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants
Defective DNA repair has a causal role in hereditary colorectal cancer (CRC). Defects in the base excision repair gene MUTYH are responsible for MUTYH-associated polyposis and CRC predisposition as an autosomal r...
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Article
Recommendations to improve identification of hereditary and familial colorectal cancer in Europe
Familial colorectal cancer (CRC) accounts for 10–15% of all CRCs. In about 5% of all cases, CRC is associated with a highly penetrant dominant inherited syndrome. The most common inherited form of non-polyposi...
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Article
Open AccessThe TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers
The TP53 pathway, in which TP53 and its negative regulator MDM2 are the central elements, has an important role in carcinogenesis, particularly in BRCA1- and BRCA2-mediated carcinogenesis. A single nucleotide pol...
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Article
Open AccessGene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis
Gene expression profiling has distinguished sporadic breast tumour classes with genetic and clinical differences. Less is known about the molecular classification of familial breast tumours, which are generall...
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Article
Kinetic study of the thermal degradation of PS/MMT nanocomposites preparedwith imidazolium surfactants
Styrene and montmorillonite organically modified with imidazolium surfactants (MMT) at various alkyl chain lengths (C12, C16 and C18) were used to prepare the corresponding PS/MMT/C12, PS/MMT/C16 and PS/MMT/C18 n...
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Article
Heat capacities of a series of terminal linear alkyldiamides determined by DSC
Molar heat capacities of twelve linear alkane-α,ω-diamides H2NOC-(CH2)(n-2)-CONH2, (n=2 to 12 and n=14) were measured by differential scanning calorimetry at T=183 to 323 K. Heat flow rate calibration of the Mett...
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Article
Serum depletion and bioavailability of lutein in Type I diabetic patients
Background Lutein, a non-provitamin A carotenoid, is frequently consumed in the human diet. It is distributed preferentially in certain human tissues (i. e., retina) and shows a high antioxidant ...
