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Article
Open AccessIL-1β and BDNF are associated with improvement in hypersomnia but not insomnia following exercise in major depressive disorder
Given the role of sleep in the development and treatment of major depressive disorder (MDD), it is becoming increasingly clear that elucidation of the biological mechanisms underlying sleep disturbances in MDD...
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Article
Recommendations to improve identification of hereditary and familial colorectal cancer in Europe
Familial colorectal cancer (CRC) accounts for 10–15% of all CRCs. In about 5% of all cases, CRC is associated with a highly penetrant dominant inherited syndrome. The most common inherited form of non-polyposi...
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Article
Optimized gene transfer into human primary leukemic T cell with NOD-SCID/leukemia-initiating cell activity
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Article
Screening for urinary tract cancer with urine cytology in Lynch syndrome and familial colorectal cancer
Aim The aim of this study was to evaluate if Urine Cytology (UC) is an appropriate screening procedure for detecting urinary tract neoplasia at an early stage in persons at risk in Heredi...
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Article
Sessile serrated polyps of the colorectum are rare in patients with Lynch syndrome and in familial colorectal cancer families
Whereas the generally accepted carcinogenesis pathway of the microsatellite instabile high (MSI-H) colorectal carcinoma (CRC) involves the traditional adenoma in patients with Lynch syndrome, a serrate pathway...
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Article
Assessment of lower urinary tract symptoms in women by a self-administered questionnaire: Test-retest reliability
A self-administered questionnaire assessing female lower urinary tract symptoms and their impact on quality of life is described and validated, on 56 females in six participating departments. The patients answ...
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Article
Ophthalmoscopy for congenital hypertrophy of the retinal pigment epithelium (CHRPE) in patients with sporadic colorectal carcinoma
In order to investigate the frequency of congenital hypertrophy of the retinal pigment epithelium (CHRPE) in sporadic colorectal cancer, ophthalmoscopy was carried out in 34 patients with colorectal carcinoma ...
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Chapter
Transplantation with Enriched Stem Cell Fractions
A technology that can be used to isolate hematopoietic progenitors will have widespread clinical applications. First, autologous marrow transplantation is finding an increasingly important role in the treatmen...
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Article
Obituary for Razia Zaman and Shahanara Zaman Saroya
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Chapter
Conditioning regimens in bone marrow transplantation
The ideal conditioning regimen for marrow transplants both destroys the underlying malignant disease and abrogates host immunity sufficiently to prevent rejection of the graft without undue toxicity. Unfortuna...