-
Article
Open AccessTargeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies
Metastatic dissemination of solid tumors, a leading cause of cancer-related mortality, underscores the urgent need for enhanced insights into the molecular and cellular mechanisms underlying metastasis, chemor...
-
Article
Open AccessFeasibility of wear reduction for soft nanostructured thin film through enhanced elastic recoverability and contact stress relief
This work shows that a soft, thin film comprising randomly aligned carbon nanotubes (CNTs) can reduce surface wear more effectively than a homogeneous thin film because of enhanced elastic recoverability and c...
-
Living Reference Work Entry In depth
Biopolymer-Based Blends
The indispensable nature of plastic-based materials in packaging processes and their widespread global dependency marks an era of a “plastic crisis” with toxicological and environmental consequences to all liv...
-
Article
Tribological characteristics of a microtextured polymer fabricated via an additive manufacturing process
With the growing interest in 3D printing, many studies are being conducted to replace conventional manufacturing processes. In terms of mechanical applications, however, research on the tribological characteri...
-
Article
Open AccessVisual feedback improves bimanual force control performances at planning and execution levels
The purpose of this study was to determine the effect of different visual conditions and targeted force levels on bilateral motor synergies and bimanual force control performances. Fourteen healthy young parti...
-
Article
Open AccessCorrection: Ablation of dynamin-related protein 1 promotes diabetes-induced synaptic injury in the hippocampus
-
Article
Open AccessAblation of dynamin-related protein 1 promotes diabetes-induced synaptic injury in the hippocampus
Dynamin-related protein 1 (Drp1)-mediated mitochondrial dysfunction is associated with synaptic injury in the diabetic brain. However, the dysfunctional mitochondria by Drp1 deletion in the diabetic brain are ...
-
Article
Open AccessTransient changes in paretic and non-paretic isometric force control during bimanual submaximal and maximal contractions
The purpose of this study was to investigate transient bimanual effects on the force control capabilities of the paretic and non-paretic arms in individuals post stroke across submaximal and maximal force cont...
-
Article
Open AccessAllergic contact dermatitis of both eyes caused by alcaftadine 0.25%: a case report
To report the first case of allergic contact dermatitis (ACD) associated with alcaftadine 0.25% ophthalmic solution.
-
Article
Open AccessInsufficient glutamine synthetase activity during synaptogenesis causes spatial memory impairment in adult mice
Glutamatergic synapses constitute a major excitatory neurotransmission system and are regulated by glutamate/glutamine (Gln) cycling between neurons and astrocytes. Gln synthetase (GS) produced by astrocytes p...
-
Article
Open AccessStudy on frictional behavior of carbon nanotube thin films with respect to surface condition
In this work, tribological characteristics of thin films composed of entangled carbon nanotubes (CNTs) were investigated. The surface roughness of CNT thin films fabricated via a dip-coating process was contro...
-
Article
Open AccessTonEBP/NFAT5 haploinsufficiency attenuates hippocampal inflammation in high-fat diet/streptozotocin-induced diabetic mice
Recent studies have shown that overexpression of tonicity-responsive enhancer binding protein (TonEBP) is associated with many inflammatory diseases, including diabetes mellitus, which causes neuroinflammation...
-
Article
Investigation of mechanical behavior of single- and multi-layer graphene by using molecular dynamics simulation
Graphene has been researched intensively due to its outstanding mechanical and electrical properties. However, understanding of its behavior in atomic scale is still lacking because of difficulties in experime...
-
Article
Fast and scalable vector similarity joins with MapReduce
Vector similarity join, which finds similar pairs of vector objects, is a computationally expensive process. As its number of vectors increases, the time needed for join operation increases proportional to the...
-
Article
Nano-lubrication: A review
Lubrication is essential for proper and reliable operation of mechanical systems as it is vital to reduce friction and wear of moving components to assure high quality performance. Particularly, with continued...
-
Article
Friction and Deformation Behaviors of ~60-μm Stainless Steel Micro-balls for Application in Small Precision Devices
The friction and deformation behaviors of ~60-μm-diameter stainless steel micro-balls were assessed under various rolling conditions against Si specimens. In the friction tests, the micro-balls were placed bet...
-
Article
Does Patient Compliance with Follow-up Influence Weight Loss After Gastric Bypass Surgery? A Systematic Review and Meta-Analysis
Gastric bypass surgery is an effective intervention to manage morbid obesity. However, there have been suggestions that patients who do not comply to follow-up lose less weight. This study evaluated the influe...
-
Article
Tribology of graphene: A review
Graphene has received significant attention due to its combination of remarkable mechanical, thermal, chemical and electrical properties. Furthermore, due to its superior strength, graphene has great potential...
-
Article
The Rho-Kinase (ROCK) Inhibitor Y-27632 Protects Against Excitotoxicity-Induced Neuronal Death In Vivo and In Vitro
Rho-associated coil kinase (ROCK) inhibitors reportedly prevent neurodegeneration, and abnormal ROCK activation in the central nervous system induces neurite collapse and retraction. However, it is unclear whe...
-
Article
Open AccessDecreased expression of extracellular matrix proteins and trophic factors in the amygdala complex of depressed mice after chronic immobilization stress
The amygdala plays an essential role in controlling emotional behaviors and has numerous connections to other brain regions. The functional role of the amygdala has been highlighted by various studies of stres...
