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  1. Article

    Open Access

    Familial clustering of dysbiotic oral and fecal microbiomes in juvenile dermatomyositis

    Juvenile dermatomyositis (JDM) is a rare immune-mediated disease of childhood with putative links to microbial exposures. In this multi-center, prospective, observational cohort study, we evaluated whether JDM...

    Sean T. Koester, Albert Chow, Evan Pepper-Tunick, Peggy Lee in Scientific Reports (2024)

  2. Article

    Open Access

    Impact of multidrug resistance on outcomes in hematologic cancer patients with bacterial bloodstream infections

    Despite the improved outcomes in patients with hematological malignancies, infections caused by multidrug-resistant organisms (MDROs) pose a new threat to these patients. We retrospectively reviewed the patien...

    Ki-Ho Park, Ye Ji Jung, Hyun Jung Lee, Hong Jun Kim, Chi Hoon Maeng in Scientific Reports (2024)

  3. No Access

    Article

    Ochratoxin A induces hepatic and renal toxicity in mice through increased oxidative stress, mitochondrial damage, and multiple cell death mechanisms

    Ochratoxin A (OTA) is a widespread food toxin produced by Aspergillus ochraceus and other molds. In this study, we developed and established acute OTA toxicity conditions in mice, which received daily oral doses ...

    Youlim Son, Hyun Jung Lee, Do** Ryu, Jae-Ryong Kim in Archives of Toxicology (2024)

  4. No Access

    Article

    Intra-articular injection of stigmasterol-loaded nanoparticles reduce pain and inhibit the inflammation and joint destruction in osteoarthritis rat model: A pilot study

    Stigmasterol, a plant-derived sterol, sharing structural similarity with cholesterol, has demonstrated anti-osteoarthritis (OA) properties, attributed to its antioxidant and anti-inflammatory capabilities. Giv...

    Ji Hyun Lim, Sung Eun Kim, Hak-Jun Kim in Drug Delivery and Translational Research (2024)

  5. Article

    Open Access

    Concordance of HER2 status between core needle biopsy and surgical resection specimens of breast cancer: an analysis focusing on the HER2-low status

    Human epidermal growth factor receptor 2 (HER2)-low status has recently gained attention because of the potential therapeutic benefits of antibody–drug conjugates (ADCs) in breast cancer patients. We aimed to ...

    Sei Na, Milim Kim, Yujun Park, Hyun Jung Kwon, Hee-Chul Shin, Eun-Kyu Kim in Breast Cancer (2024)

  6. Article

    Open Access

    2023 Korean Society of Echocardiography position paper for the diagnosis and management of valvular heart disease, part II: mitral and tricuspid valve disease

    This manuscript represents the official position of the Korean Society of Echocardiography on valvular heart diseases. This position paper focuses on the diagnosis and management of valvular heart diseases wit...

    Chi Young Shim, Eun Kyoung Kim, Dong-Hyuk Cho in Journal of Cardiovascular Imaging (2024)

  7. Article

    Open Access

    Decreased aggressive care at the end of life among advanced cancer patients in the Republic of Korea: a nationwide study from 2012 to 2018

    This study aimed to investigate the trends of aggressive care at the end-of-life (EoL) for patients with advanced cancer in Korea and to identify factors affecting such care analyzing nationwide data between 2...

    Sara Kwon, Kyuwoong Kim, Bohyun Park, So-Jung Park, Hyun Jung Jho in BMC Palliative Care (2024)

  8. Article

    Open Access

    Assessment of malignant potential for HPV types 16, 52, and 58 in the uterine cervix within a Korean cohort

    High-risk human papillomavirus (HR-HPV) is the primary carcinogen in uterine cervical carcinoma. While genotype-specific carcinogenic risks have been extensively studied in Western populations, data from Korea...

    Juhun Lee, Dong Ja Kim, Hyun Jung Lee in Scientific Reports (2024)

  9. Article

    Open Access

    Vimentin-mediated buffering of internal integrin β1 pool increases survival of cells from anoikis

    The intermediate filament protein vimentin is widely recognized as a molecular marker of epithelial-to-mesenchymal transition. Although vimentin expression is strongly associated with cancer metastatic potenti...

    Jiyoung Jang, Hyun Jung Park, Wonyoung Seong, Jiyoon Kim, Chungho Kim in BMC Biology (2024)

  10. Article

    Open Access

    Cardiovascular disease risk and associated physical activity factors in gastrointestinal cancer survivors

    Although the risk of CVD is increased in cancer survivors, few studies have investigated the CVD risk in survivors of gastrointestinal (GI) cancer. Therefore, we evaluated the CVD risk using the 10-year athero...

    Su Young Kim, Hye Jung Kang, Ki-Hyun Kim, Dong Uk Kim, Seung-Joo Nam in BMC Public Health (2024)

  11. Article

    Open Access

    Desensitizing efficacy of a universal dentin adhesive containing mesoporous bioactive glass on dentin hypersensitivity: a randomized clinical trial with a split-mouth model

    This split-mouth blinded randomized controlled study compared the efficacy of a desensitizing agent with oxalate/resin polymer and a universal adhesive containing mesoporous bioactive glass (MBG) for dentin hy...

    Hyun-Jung Kim, Soram Oh, Jiyoung Kwon, Kyoung-Kyu Choi, Ji-Hyun Jang in Scientific Reports (2024)

  12. Article

    Open Access

    Molecular mechanisms of circular RNA translation

    Circular RNAs (circRNAs) are covalently closed single-stranded RNAs without a 5′ cap structure and a 3′ poly(A) tail typically present in linear mRNAs of eukaryotic cells. CircRNAs are predominantly generated ...

    Hyun Jung Hwang, Yoon Ki Kim in Experimental & Molecular Medicine (2024)

  13. No Access

    Article

    Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma

    Symptoms are important components in determining asthma control and in the adjustment of treatment levels. However, clinical relevance of cough in severe asthma is not well-understood. This study aimed to eval...

    Hwa Young Lee, Youngsoo Lee, Ji-Hyang Lee, Seung-Eun Lee, Da Woon Sim, Noeul Kang in Lung (2024)

  14. No Access

    Article

    Sacubitril/valsartan and the risk of incident dementia in heart failure: a nationwide propensity-matched cohort study

    Sacubitril acts to inhibit neprilysin and as neprilysin is involved in amyloid-beta degradation in the central nervous system, and there is concern that sacubitril/valsartan may increase the risk of dementia. ...

    Hyun-Jung Lee, Hyung-Kwan Kim, Bong-Seong Kim in Clinical Research in Cardiology (2024)

  15. No Access

    Article

    Evaluating the Accuracy of Machine Learning Classification Models for Similar Herbal Medicine Using Hyperspectral Imaging

    Processed herbal medicines in East Asia are often misused or mixed because distinguishing their different forms is difficult using the naked eye. However, an artificial intelligence model can address this prob...

    So ** Park, Hyo In Yoon, Hyein Lee, Min-Chae Kim in Journal of Biosystems Engineering (2024)

  16. No Access

    Article

    Do Divine Struggles Moderate the Association Between Interpersonal Conflict at Work and Worker Well-Being in Singapore?

    The purpose of this study is to examine how divine struggles moderate the association between interpersonal workplace conflict and worker well-being in Singapore. Using data from the Work, Religion, and Health...

    Jong Hyun Jung, Shi Hui Joy Soo, Shannon Ang in Journal of Religion and Health (2024)

  17. No Access

    Article

    How Do Students Respond to the Intended Affordance of Augmented Reality Dinosaur Exhibits in a Science Museum?

    As augmented reality (AR) gains prevalence, various AR exhibits are being installed in science museums. However, few research has thus far examined the extent to which these exhibits can improve visitors’ lear...

    Seok-Hyun Ga, Hyun-Jung Cha, Hye-Gyoung Yoon in Journal of Science Education and Technology (2024)

  18. Article

    Open Access

    Prediction of TKI response in EGFR-mutant lung cancer patients-derived organoids using malignant pleural effusion

    Patient-derived organoids (PDOs) are valuable in predicting response to cancer therapy. PDOs are ideal models for precision oncologists. However, their practical application in guiding timely clinical decision...

    Sang-Hyun Lee, Kyuhwan Kim, Eunyoung Lee, Kyungmin Lee in npj Precision Oncology (2024)

  19. Article

    Open Access

    Tuberculous pleural effusion-induced Arg-1+ macrophage polarization contributes to lung cancer progression via autophagy signaling

    The association between tuberculous fibrosis and lung cancer development has been reported by some epidemiological and experimental studies; however, its underlying mechanisms remain unclear, and the role of m...

    Seong Ji Woo, Youngmi Kim, Hyun-Jung Kang, Harry Jung in Respiratory Research (2024)

  20. No Access

    Article

    Relation between textural attributes and surface leachate structural and compositional characteristics of cooked rice

    The objective of this study was to evaluate the leachate and textural characteristics of cooked rice, and the correlations between the leachate properties and texture attributes were also investigated. Cooked ...

    Mingyo Ha, Duyun Jeong, Jiyoung Park, Hyun-Jung Chung in Food Science and Biotechnology (2024)

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