-
Article
Open AccessInitial lactate levels linked to oliguria in term neonates with perinatal asphyxia
Oliguria is a sign of impaired kidney function and has been shown to be an early predictor of adverse prognoses in patients with acute kidney injury. The relationship between urine output (UOP) and early lacta...
-
Article
Open AccessEarly smoking lead to worse prognosis of COPD patients: a real world study
Smoking remains a major risk factor for the development and progression of chronic obstructive pulmonary disease (COPD). Due to the adolescent smoking associated with worse health state, the age, at which an i...
-
Article
Open AccessNemonoxacin achieved a better symptomatic improvement and a prolonged interval to next exacerbation than moxifloxacin for outpatients with acute exacerbations of chronic obstructive pulmonary disease
Nemonoxacin is a novel non-fluorinated quinolone with strong antibacterial efficacy, but data of its effect on acute exacerbations of chronic obstructive pulmonary disease (AECOPD) is rare. This study was cond...
-
Article
Open AccessMFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells
Milk fat globule epidermal growth factor 8 (MFG-E8) participates in a range of cellular processes, including reducing apoptosis and oxidative stress. However, its protective activity against cigarette smoke-in...
-
Article
Open AccessLong noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD
To study the regulatory effect of Long non-coding RNA (LncRNA) HOX transcript antisense RNA (HOTAIR) on pulmonary vascular endothelial cell (HPVEC) apoptosis and determine whether the HOTAIR facilitate HPVEC a...
-
Article
Time-asymptotics of physical vacuum free boundaries for compressible inviscid flows with dam**
In this paper, we prove the leading term of time-asymptotics of the moving vacuum boundary for compressible inviscid flows with dam** to be that for Barenblatt self-similar solutions to the corresponding por...
-
Article
Open AccessSubgroup analysis reveals higher reliability of the new comprehensive evaluation of Global Initiative for Chronic Obstructive Lung Disease 2019
To estimate the severity of the disease in outpatients with chronic obstructive pulmonary disease (COPD) in Hunan Province, China and use the subgroup analysis to evaluate the reliability of the new comprehens...
-
Article
On the Free Surface Motion of Highly Subsonic Heat-Conducting Inviscid Flows
For the free surface problem of highly subsonic heat-conducting inviscid flow in 2-D and 3-D, a priori estimates for geometric quantities of free surfaces, such as the second fundamental form and the injectivity ...
-
Article
Magnetic graphene-based nanocomposites as highly efficient absorbents for Cr(VI) removal from wastewater
Due to the merits of their high adsorption and convenient separation, magnetic graphene-based composites have become a promising adsorbent in terms of wastewater treatment. However, recycling and regeneration ...
-
Article
Almost Global Solutions to the Three-Dimensional Isentropic Inviscid Flows with Dam** in a Physical Vacuum Around Barenlatt Solutions
For the three-dimensional vacuum free boundary problem with physical singularity where the sound speed is \(C^{1/2}\) ...
-
Article
Open AccessSNORA71B promotes breast cancer cells across blood–brain barrier by inducing epithelial-mesenchymal transition
Brain metastasis (BM) is a dreadful complication that significantly impacts the quality of life in breast cancer patients. A key process during brain metastasis is the migration of cancer cells across blood–br...
-
Article
Open AccessOxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model
Emphysema is a crucial pathological characteristic of chronic obstructive pulmonary disease (COPD). Oxidative stress, apoptosis and epigenetic mechanisms contribute to the pathogenesis of emphysema. However, a...
-
Article
Open AccessPerinatal listeriosis patients treated at a maternity hospital in Bei**g, China, from 2013–2018
Listeriosis is a rare but severe foodborne infectious disease. Perinatal listeriosis is often associated with septicemia, central nervous system (CNS) infection, and serious adverse pregnancy outcomes (miscarr...
-
Article
Effects of a formula with a probiotic Bifidobacterium lactis Supplement on the gut microbiota of low birth weight infants
Low birth weight (LBW) infants have a less diverse gut microbiota, enriched in potential pathogens, which places them at high risk of systemic inflammation diseases. This study aimed to identify the difference...
-
Article
Open AccessThioredoxin Reductase as a Novel and Efficient Plasma Biomarker for the Detection of Non-Small Cell Lung Cancer: a Large-scale, Multicenter study
There is an increased demand for efficient biomarkers for the diagnosis of non-small cell lung cancer (NSCLC). This study aimed to evaluate plasma levels of TrxR activity in a large population to confirm its v...
-
Article
Global Resolution of the Physical Vacuum Singularity for Three-Dimensional Isentropic Inviscid Flows with Dam** in Spherically Symmetric Motions
For the gas–vacuum interface problem with physical singularity and the sound speed being \({C^{{1}/{2}}}\) ...
-
Article
Open AccessRole of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stress
Thioredoxin reductase 1 (TrxR1) is a pivotal intracellular redox sensor and antioxidant enzyme. On the other hand, overexpression of TrxR1 is closely correlated with the initiation of various tumors including ...
-
Article
Nonlinear Asymptotic Stability of the Lane-Emden Solutions for the Viscous Gaseous Star Problem with Degenerate Density Dependent Viscosities
The nonlinear asymptotic stability of Lane-Emden solutions is proved in this paper for spherically symmetric motions of viscous gaseous stars with the density dependent shear and bulk viscosities which vanish ...
-
Article
Well-Posedness for the Motion of Physical Vacuum of the Three-dimensional Compressible Euler Equations with or without Self-Gravitation
This paper concerns the well-posedness theory of the motion of a physical vacuum for the compressible Euler equations with or without self-gravitation. First, a general uniqueness theorem of classical solution...
-
Article
Multidimensional stability of traveling fronts in monostable reaction-diffusion equations with complex perturbations
This paper studies the multidimensional stability of traveling fronts in monostable reaction-diffusion equations, including Ginzburg-Landau equations and Fisher-KPP equations. Eckmann andWayne (1994) showed a ...
