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    Upregulated Expression of TRIM32 Is Involved in Schwann Cell Differentiation, Migration and Neurite Outgrowth After Sciatic Nerve Crush

    Tripartite motif containing 32 (TRIM32), a member of the tripartite motif (TRIM) family, plays an indispensable role in myoblast proliferation. It also regulates neuron and skeletal muscle stem cell differenti...

    Yonghua Liu, Weijie Wu, Huiguang Yang, Zhengming Zhou in Neurochemical Research (2017)

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    SCY1-Like 1-Binding Protein 1 (SCYL1BP1) Suppressed Sciatic Nerve Regeneration by Enhancing the RhoA Pathway

    SCY1-like 1-binding protein 1 (SCYL1BP1) is first identified as an interacting protein with SCYL1. Since SCYL1BP1 is a soluble protein with coiled-coil domains known to be relevant with transcriptional regulat...

    Weidong Zhang, Yonghua Liu, Xudong Zhu, Yi Cao, Yang Liu in Molecular Neurobiology (2016)

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    Involvement of Upregulated SYF2 in Schwann Cell Differentiation and Migration After Sciatic Nerve Crush

    SYF2 is a putative homolog of human p29 in Saccharomyces cerevisiae. It seems to be involved in pre-mRNA splicing and cell cycle progression. Disruption of SYF2 leads to reduced α-tubulin expression and delayed n...

    Zhengming Zhou, Yang Liu, **aoke Nie, Jianhua Cao in Cellular and Molecular Neurobiology (2014)

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    β-1,4-Galactosyltransferase I Promotes Tumor Necrosis Factor-α Autocrine via the Activation of MAP Kinase Signal Pathways in Schwann Cells

    Recent studies have demonstrated that aberrant galactosylation is associated with some inflammation diseases. β-1,4-Galactosyltransferase-I (β-1,4-GalT I), which transferred galactose to the terminal N-acetylg...

    Huiguang Yang, Qin Yuan, Qian Chen, Chunmiao Li in Journal of Molecular Neuroscience (2011)

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    The Cyclin-Dependent Kinase Inhibitor p27Kip1 is a Positive Regulator of Schwann Cell Differentiation In Vitro

    Schwann cell precursors differentiating into a myelinating phenotype are critical for peripheral nerve development and regeneration. However, little is known about the underlying molecular mechanisms of Schwan...

    Honghui Li, Huiguang Yang, Yonghua Liu, Weipeng Huan in Journal of Molecular Neuroscience (2011)

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    An Upregulation of SIAH1 After Spinal Cord Injury in Adult Rats

    E3 ubiquitin ligase SIAH1 is a protein associated with the onset of nontumorigenicy in revertant tumorigenic cell lines and with several apoptotic processes. However, its role in the injury of the central nerv...

    Donglin Wang, Qiuhui Lu, Bai Shao, Gang Cui in Journal of Molecular Neuroscience (2011)

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    The Relationship Between Src-Suppressed C Kinase Substrate and β-1,4 Galactosyltransferase-I in the Process of Lipopolysaccharide-Induced TNF-α Secretion in Rat Primary Astrocytes

    Src-suppressed C kinase substrate (SSeCKS), a protein kinase C substrate, is a major lipopolysaccharide (LPS) response protein. In addition, β-1,4 Galactosyltransferase-I (β-1,4-GalT-I) also plays an important...

    Bai Shao, Chunmiao Li, Huiguang Yang, Aiguo Shen in Cellular and Molecular Neurobiology (2011)

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    Temporal and Spatial Expression of Cyclin H in Rat Spinal Cord Injury

    Cyclin H regulates cell cycle transitions; it always forms trimeric cyclin-dependent protein kinases (CDK)-activating kinase (CAK) complex with CDK7 and MAT1 that phosphorylates a threonine residue in the CDK2...

    Gang Wu, Jianhua Cao, Chen Peng, Huiguang Yang, Zhiming Cui in NeuroMolecular Medicine (2011)

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    Expressions of Forkhead Class Box O 3a on Crushed Rat Sciatic Nerves and Differentiated Primary Schwann cells

    Forkhead box-containing protein, class O 3 a (FOXO3a), an Akt downstream target, plays an important role in peripheral nervous system. FOXO3a shares the ability to be inhibited and translocated from the nucleu...

    Qiuhong Wang, Youhua Wang, Zhengming Zhou, **ang Lu in Cellular and Molecular Neurobiology (2011)

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    SSeCKS Promotes Tumor Necrosis Factor-α Autocrine via Activating p38 and JNK Pathways in Schwann Cells

    Tumor necrosis factor-alpha (TNF-α) derived from activated Schwann cells (SCs) plays a critical role as an inflammatory mediator in the peripheral nervous system disease. TNF-α could act as an autocrine mediat...

    Zhengming Zhou, Tao Tao, Yuhong Ji, Huiguang Yang in Cellular and Molecular Neurobiology (2010)

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    SSeCKS is a Suppressor in Schwann Cell Differentiation and Myelination

    Src-suppressed protein kinase C substrate (SSeCKS) plays an important role in the differentiation process. In regeneration of sciatic nerve injury, expression of SSeCKS decreases, mainly in Schwann cells. Howe...

    Yuhong Ji, Tao Tao, Chun Cheng, Huiguang Yang, Youhua Wang in Neurochemical Research (2010)