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  1. Article

    Open Access

    LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy

    Diabetic nephropathy (DN) as the primary cause of end-stage kidney disease is a common complication of diabetes. Recent researches have shown the activation of nuclear factor kappa light-chain enhancer of acti...

    Hong Yi, Rui Peng, Lu-yu Zhang, Yan Sun, Hui-min Peng, Han-deng Liu… in Cell Death & Disease (2017)

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    Article

    The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice

    Down-regulation of let-7 microRNA (miRNA) plays an important role in the pathogenesis of lung cancer. k-Ras and c-Myc, two key oncogenes in lung cancer, have been found to be targeted by let-7 in vitro. Howeve...

    **ao-yan He, Jun-xia Chen, Zheng Zhang… in Journal of Cancer Research and Clinical On… (2010)