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  1. Article

    Open Access

    Gut microbiota affects the estrus return of sows by regulating the metabolism of sex steroid hormones

    Sex hormones play important roles in the estrus return of post-weaning sows. Previous studies have demonstrated a complex and bi-directional regulation between sex hormones and gut microbiota. However, the ext...

    Min Liu, Jia Zhang, Yunyan Zhou, Shuqi **ong in Journal of Animal Science and Biotechnology (2023)

  2. Article

    Open Access

    Author Correction: Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling

    Ying Yu, Wanwan Hou, Yaqing Liu, Haiyan Wang, Lianhua Dong in Nature Biotechnology (2023)

  3. Article

    Open Access

    Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling

    Certified RNA reference materials are indispensable for assessing the reliability of RNA sequencing to detect intrinsically small biological differences in clinical settings, such as molecular subty** of dis...

    Ying Yu, Wanwan Hou, Yaqing Liu, Haiyan Wang, Lianhua Dong in Nature Biotechnology (2023)

  4. Article

    Open Access

    Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials

    Characterization and integration of the genome, epigenome, transcriptome, proteome and metabolome of different datasets is difficult owing to a lack of ground truth. Here we develop and characterize suites of ...

    Yuanting Zheng, Yaqing Liu, **gcheng Yang, Lianhua Dong, Rui Zhang in Nature Biotechnology (2023)

  5. No Access

    Article

    The Pseudogene BMEA_B0173 Deficiency in Brucella melitensis Contributes to M-epitope Formation and Potentiates Virulence in a Mice Infection Model

    It is widely acknowledged that pseudogenes play important roles in bacterial diversification and evolution and participate in gene regulation and RNA interference (RNAi). However, the function of most pseudoge...

    Ge Zhang, Hao Dong, Yu Feng, Hui Jiang, Tonglei Wu, Jiali Sun in Current Microbiology (2022)

  6. Article

    Open Access

    Identification of the sesquiterpene synthase AcTPS1 and high production of (–)-germacrene D in metabolically engineered Saccharomyces cerevisiae

    The sesquiterpene germacrene D is a highly promising product due to its wide variety of insecticidal activities and ability to serve as a precursor for many other sesquiterpenes. Biosynthesis of high value com...

    Jiajia Liu, Chang Chen, **ukun Wan, Ge Yao, Shaoheng Bao in Microbial Cell Factories (2022)

  7. No Access

    Article

    Intelligent bio-assembly imaging-guided platform for real-time bacteria sterilizing and infectious therapy

    Bacterial infection is rising as a threatening health issue. Because of the present delay in early diagnosis of bacterial diseases as well as the abuse of antibiotics, it has become a vital issue in the develo...

    Jiayu Zeng, Zengchao Guo, Yihan Wang, Zhaojian Qin, Yi Ma, Hui Jiang in Nano Research (2022)

  8. No Access

    Article

    Metabolic pathway analysis of walnut endophytic bacterium Bacillus subtilis HB1310 related to lipid production from fermentation of cotton stalk hydrolysate based on genome sequencing

    In this study, genome sequencing and metabolic analysis were used to identify and verify the key metabolic pathways for glucose and xylose utilization and fatty acid synthesis in the walnut endophytic bacteriu...

    Qin Zhang, Panpan Liu, Yanbin Li, Hui Jiang in Biotechnology Letters (2021)

  9. No Access

    Article

    Deep sequencing of the Sanghuangporus vaninii transcriptome reveals dynamic landscapes of candidate genes involved in the biosynthesis of active compounds

    The medicinal fungus Sanghuang produces diverse bioactive compounds and is widely used in Asian countries. However, little is known about the genes and pathways involved in the biosynthesis of these active compou...

    Qiumei Zhou, Jiuxiang Wang, Hui Jiang, Gaofei Wang, Yulong Wang in Archives of Microbiology (2021)

  10. No Access

    Article

    Strategies for Discovering New Antibiotics from Bacteria in the Post-Genomic Era

    New antibiotics are urgently required in clinical treatment and agriculture with the development of antimicrobial resistance. However, products discovered by repeating previous strategies are either not antibi...

    Jia-Wei Zhu, Si-Jia Zhang, Wen-Guang Wang, Hui Jiang in Current Microbiology (2020)

  11. Article

    Open Access

    Enhanced biohydrogen production from cotton stalk hydrolysate of Enterobacter cloacae WL1318 by overexpression of the formate hydrogen lyase activator gene

    Biohydrogen production from lignocellulose has become an important hydrogen production method due to its diversity, renewability, and cheapness. Overexpression of the formate hydrogen lyase activator (fhlA) gene ...

    Qin Zhang, Shaolin You, Yanbin Li, **aowei Qu, Hui Jiang in Biotechnology for Biofuels (2020)

  12. Article

    Open Access

    A simple method for in vitro preparation of natural killer cells from cord blood

    Cord Blood (CB) has been considered a promising source of natural killer (NK) cells for cellular immunotherapy. However, it is difficult to expand the large numbers of highly pure NK cells from CB without cell...

    Yong Xu Mu, Yu **a Zhao, Bing Yao Li, Hong **g Bao, Hui Jiang in BMC Biotechnology (2019)

  13. No Access

    Article

    Bacillus subtilis Spore Surface Display of Haloalkane Dehalogenase DhaA

    The haloalkane dehalogenase DhaA can degrade sulfur mustard (2,2′-dichlorethyl sulfide; also known by its military designation HD) in a rapid and environmentally safe manner. However, DhaA is sensitive to temp...

    Fuli Wang, Tianyu Song, Hui Jiang, Chengxin Pei, Qibin Huang in Current Microbiology (2019)

  14. No Access

    Article

    New two-component regulatory system required for the constitutive expression of bph operon in Cupriavidus basilensis WS

    Cupriavidus basilensis WS degrades diphenyl ether (DE) and its lower brominated derivatives using enzymes encoded by the bph operon. However, it is not yet known under what circumstances bph genes are expressed a...

    Sheng Wang, Yajun Li, Bing Wang, Linna Du in Applied Microbiology and Biotechnology (2019)

  15. Article

    Erratum: Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling

    Nat. Biotechnol. 10.1038/nbt.4183; corrected online 31 July 2018 In the version of this article initially published online, the text “Beth Israel Deaconess Medical Center/Dana Farber Cancer Institute (BIDMC/DF...

    Maria D Giraldez, Ryan M Spengler, Alton Etheridge, Paula M Godoy in Nature Biotechnology (2018)

  16. No Access

    Article

    Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling

    Systematic evaluation of library preparation methods for small RNA-seq identifies reproducible and accurate methods.

    Maria D Giraldez, Ryan M Spengler, Alton Etheridge, Paula M Godoy in Nature Biotechnology (2018)

  17. No Access

    Article

    Biohydrogen production from fermentation of cotton stalk hydrolysate by Klebsiella sp. WL1316 newly isolated from wild carp (Cyprinus carpio L.) of the Tarim River basin

    A new hydrogen-producing bacterium was isolated from the intestine of wild carp (Cyprinus carpio L.) of the Tarim River Basin. The isolate was identified as Klebsiella sp. based on 16S rDNA gene sequencing and ex...

    Yanbin Li, Qin Zhang, Li Deng, Zhanwen Liu in Applied Microbiology and Biotechnology (2018)

  18. No Access

    Article

    Co-cultured the MSCs and cardiomyocytes can promote the growth of cardiomyocytes

    Recently, the incidence of myocardial infarction has been increasing annually. Now cell therapy is a major new strategy in the treatment of this public health challenge. Most recently, evidences showed that MS...

    Hui Jiang, Huishan Wang, Tao Liu, Zhonglu Yang, Renteng Zhang in Cytotechnology (2018)

  19. No Access

    Article

    Design of dual metal ions/dual amino acids integrated photoluminescent logic gate by high-molecular weight protein-localized Au nanoclusters

    Proteins are excellent templates and stabilizers for Au nanoclusters (NCs) because of their abundant thiol groups and unique internal environments. However, high-molecular weight (MW) proteins with special qua...

    Liu Liu, Hui Jiang, Xuemei Wang in Nano Research (2018)

  20. No Access

    Article

    Rapid and multimodal in vivo bioimaging of cancer cells through in situ biosynthesis of Zn&Fe nanoclusters

    Early diagnosis remains highly important for efficient cancer treatment, and hence, there is significant interest in the development of effective imaging strategies. This work reports a new multimodal bioimagi...

    Tianyu Du, Chunqiu Zhao, Fawad ur Rehman, Lanmei Lai, **aoqi Li, Yi Sun in Nano Research (2017)

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