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Article
Open AccessAuthor Correction: Distinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy
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Article
Effects of Deformation Mechanisms on Texture Evolution and Mechanical Response of the Mg-1Al-0.5Mn-0.3Gd Alloy Under Plane Tension
The tensile plastic deformation of the Mg-1Al-0.5Mn-0.3Gd alloy with transverse direction (TD)-tilted texture have been investigated using the experimental and visco-plastic self-consistent model. The results ...
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Article
Isavuconazole Induces Neurodevelopment Defects and Motor Behaviour Impairment in Zebrafish Larvae
Isavuconazole is a broad-spectrum antifungal drug used for the treatment of serious infections caused by invasive aspergillosis and mucormycosis in adults. With the continuous use of this drug, its safety and ...
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Article
BPA induces hepatotoxicity in zebrafish through oxidative stress and apoptosis pathways
BPA is so ubiquitous that 27 million tons of BPA-containing plastic, including mineral water bottles and baby bottles, is produced worldwide each year. The potential toxicity of BPA to humans and aquatic organ...
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Article
Borneol Induced Hepatotoxicity via Caspase-3 and Oxidative Stress Pathwaysin in Zebrafish
Objective: Borneol is a widely used Chinese medicine, and borneol extracted from plants or synthesized are the two major types of borneol applied in clinical therapy. In this study, the hepatotoxicity of natural ...
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Article
Benomyl-induced development and cardiac toxicity in zebrafish embryos
Benomyl is a highly effective broad-spectrum fungicide widely used worldwide to control vegetable, fruit, and oil crop diseases. However, the mechanism of its toxicity to aquatic organisms and humans remains u...
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Article
Open AccessWuliangye Baijiu but not ethanol reduces cardiovascular disease risks in a zebrafish thrombosis model
Understanding how Baijiu facilitates blood circulation and prevents blood stasis is crucial for revealing the mechanism of Baijiu for cardiovascular disease (CVD) risk reduction. Here we established a zebrafish t...
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Article
Pamiparib Induces Neurodevelopmental Defects and Cerebral Haemorrhage in Zebrafish Embryos via Inhibiting Notch Signalling
Pamiparib is a poly ADP-ribose polymerase (PARP) inhibitor used in clinical studies, which can penetrate the blood–brain barrier efficiently. At present, there are few studies on its effect on vertebrate neuro...
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Article
Notes on Hypercyclicity of Composition Operator on the Weighted Dirichlet Spaces
In this paper, the hypercyclic behavior of multiples of composition operators induced by linear fractional self-maps of unit disk on the weighted Dirichlet spaces
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Article
Open AccessDistinct molecular and immune hallmarks of inflammatory arthritis induced by immune checkpoint inhibitors for cancer therapy
Immune checkpoint inhibitors are associated with immune-related adverse events (irAEs), including arthritis (arthritis-irAE). Management of arthritis-irAE is challenging because immunomodulatory therapy for ar...
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Article
Open AccessEfficacy of Naoxueshu in acute spontaneous intracerebral hemorrhage: a multicenter observational study
To evaluate the efficacy and safety outcome and related risk factors of Naoxueshu in the treatment of acute SICH.
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Chapter
Rheumatology (Arthritis and Myositis)
Rheumatic immune-related adverse events (irAEs) associated with immune checkpoint inhibitor (ICI) therapy in patients with cancer can be grouped into articular, muscular, granulomatous, vasculitic, and other s...
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Article
Open AccessTwo novel compound heterozygous mutations in NGLY1as a cause of congenital disorder of deglycosylation: a case presentation
NGLY1-related congenital disorder of deglycosylation (NGLY1-CDDG) is a multisystemic neurodevelopmental disorder in which affected individuals show developmental delay, epilepsy, intellectual disability, abnor...
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Article
Open AccessIdentification of 12 cancer types through genome deep learning
Cancer is a major cause of death worldwide, and an early diagnosis is required for a favorable prognosis. Histological examination is the gold standard for cancer identification; however, large amount of inter...
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Article
Open AccessNephrotoxicity of immune checkpoint inhibitors beyond tubulointerstitial nephritis: single-center experience
The approved therapeutic indication for immune checkpoint inhibitors (CPIs) are rapidly expanding including treatment in the adjuvant setting, the immune related toxicities associated with CPI can limit the ef...
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Article
Fracture risk prediction using FRAX in patients following hematopoietic stem cell transplantation
We aimed to study the utility of the FRAX tool in predicting fractures in patient’s receiving a hematopoietic stem cell transplantation (HSCT). Our results indicate that the FRAX tool has modest fracture predi...
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Chapter and Conference Paper
Research on Presswork to eBook Conversion Method
The paper provides a method and computer system for providing digital content of a presswork. A request is received from a sending computer by a recording device for the recording device to generate a digital ...
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Article
Expression and antigen activity determination of human thyroid peroxidase in silkworm and yeast
In this study, we report the expression of human thyroid peroxidase (TPO) in silkworm larvae and Pichia pastoris GS115. Recombinant TPO is sequentially purified from the hemolymph of infected silkworm larvae and ...
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Chapter and Conference Paper
Effect of Extrusion Speed on the Microstructures and Mechanical Properties of Ti-6Al-4V Alloy Prepared by Combining of Powder Compact Hot Pressing and Extrusion under Air
Titanium alloys are very promising materials which can be used in the area of aerospace, marine and chemical engineering, biological engineering, etc., due to its advantage of low density, high strength, and e...
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Chapter and Conference Paper
Interconnection Power Converter for Multi-Rail DC Distribution System
This paper presents an interconnection bi-directional dc-dc converter for multi-rail DC distribution system. The principles of the energy conversion process, small signal modeling and controller design for the...
