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Article
Risk Factors for Hepatic Hydrothorax in Cirrhosis Patients with Ascites – A Clinical Cohort Study
The risk factors for hepatic hydrothorax are unknown.
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Article
Open AccessTender and swollen joint counts are poorly associated with disability in chikungunya arthritis compared to rheumatoid arthritis
Chronic rheumatological manifestations similar to those of rheumatoid arthritis (RA) are described after chikungunya virus infection. We aimed to compare the relevance of joint counts and symptoms to clinical ...
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Article
Persistent chikungunya arthritis in Roraima, Brazil
The Amazon region of Brazil experienced a large epidemic of East Central South African (ECSA) chikungunya virus (CHIKV) in 2017 and continuous transmission of CHIKV persists. The impact of chronic arthritis ca...
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Article
Stiffness, pain, and joint counts in chronic chikungunya disease: relevance to disability and quality of life
To characterize the importance of musculoskeletal stiffness in a cohort of chikungunya patients with chronic joint symptoms.
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Article
Open AccessEpilepsy as a risk factor for hepatic encephalopathy in patients with cirrhosis: a cohort study
Epilepsy is associated with an increased mortality among cirrhosis patients, but the reasons are unknown. We aimed to determine whether epilepsy is a risk factor for develo** hepatic encephalopathy (HE), whi...
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Article
Satavaptan treatment for ascites in patients with cirrhosis: a meta-analysis of effect on hepatic encephalopathy development
Satavaptan, a vasopressin V2-receptor antagonist, has been shown to improve hyponatraemia in patients with cirrhosis. Hyponatraemia has been associated with an increased risk of hepatic encephalopathy. The object...
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Article
Incorporating Affiliates and Contract Research Organizations into Global Clinical Trials
Globalization of clinical trials, and the complexity surrounding the execution of these trials, has stimulated pharmaceutical companies to review their decision making processes to include input from affiliate...