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Article
A disulfiram derivative against lung cancer via the Notch signaling pathway without neurotoxicity and hepatotoxicity
The exploration of novel anti-lung cancer small-molecule drugs is important for drug resistance and adverse effects of chemotherapeutic drugs in current clinics. Disulfiram (DSF), as an antidote, has been prov...
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Article
Open AccessTargeted delivery of HSP90 inhibitors for efficient therapy of CD44-positive acute myeloid leukemia and solid tumor-colon cancer
Heat shock protein 90 (HSP90) is overexpressed in numerous cancers, promotes the maturation of numerous oncoproteins and facilitates cancer cell growth. Certain HSP90 inhibitors have entered clinical trials. A...
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Article
Open AccessEffect of the epiphytic bacterium Bacillus sp. WPySW2 on the metabolism of Pyropia haitanensis
A variety of different symbiotic microbial communities are harbored on the surface of seaweeds, the interactions of which depend upon nutritional exchanges between the microbes and the hosts. Metabolomic profi...
