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  1. Article

    Open Access

    Surgical outcomes and risk factors for surgical complications after en bloc resection following reconstruction with 3D-printed artificial vertebral body for thoracolumbar tumors

    The outcomes of patients with tumors of the thoracolumbar spine treated with en bloc resection (EBR) using three-dimensional (3D)-printed endoprostheses are underreported.

    **xin Hu, Guohui Song, Hongmin Chen, Huaiyuan Xu in World Journal of Surgical Oncology (2023)

  2. Article

    Open Access

    Correction: NIR-II-absorbing diimmonium polymer agent achieves excellent photothermal therapy with induction of tumor immunogenic cell death

    Han Xu, Hua** Deng, **aoqian Ma, Yushuo Feng, Ruizhen Jia in Journal of Nanobiotechnology (2023)

  3. Article

    Open Access

    NIR-II-absorbing diimmonium polymer agent achieves excellent photothermal therapy with induction of tumor immunogenic cell death

    Photothermal therapy has shown great promise for cancer treatment and second near-infrared (NIR-II) -absorbing particles could further improve its precision and applicability due to its superior penetration de...

    Han Xu, Hua** Deng, **aoqian Ma, Yushuo Feng, Ruizhen Jia in Journal of Nanobiotechnology (2023)

  4. Article

    Open Access

    Identification of the miRNA-mRNA regulatory network associated with radiosensitivity in esophageal cancer based on integrative analysis of the TCGA and GEO data

    The current study set out to identify the miRNA-mRNA regulatory networks that influence the radiosensitivity in esophageal cancer based on the The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GE...

    Hongmin Chen, **aoxiao Shi, Li Ren, Hongyu Zhuo, Li Zeng, Qing Qin in BMC Medical Genomics (2022)

  5. No Access

    Article

    Regulating Synthesis of TiO2/CQDS Composite Photocatalysts and Photodegradation of DMSO in Aqueous Suspension

    A simple sol–gel method combined with hydrothermal synthesis technique were used to synthesize the rutile TiO2 nanoparticles without any other impurities and TiO2/carbon quantum dots (CQDS) composite photocatalys...

    **xi Li, **angting Dong, Hongmin Chen in Russian Journal of Physical Chemistry A (2022)

  6. Article

    Open Access

    Organic phosphorescent nanoscintillator for low-dose X-ray-induced photodynamic therapy

    X-ray-induced photodynamic therapy utilizes penetrating X-rays to activate reactive oxygen species in deep tissues for cancer treatment, which combines the advantages of photodynamic therapy and radiotherapy. ...

    **ao Wang, Wen**g Sun, Huifang Shi, Huili Ma, Guowei Niu in Nature Communications (2022)

  7. Article

    Open Access

    Composition tunability of semiconductor radiosensitizers for low-dose X-ray induced photodynamic therapy

    Radiation therapy is one of the most commonly used methods in clinical cancer treatment, and radiosensitizers could achieve enhanced therapeutic efficacy by incorporating heavy elements into structures. Howeve...

    Lei Chen, **ghui Zhang, Lihua Xu, Luchao Zhu, **peng **g in Journal of Nanobiotechnology (2022)

  8. Article

    Open Access

    Intracellular marriage of bicarbonate and Mn ions as “immune ion reactors” to regulate redox homeostasis and enhanced antitumor immune responses

    Different from Fe ions in Fenton reaction, Mn ions can function both as catalyst for chemodynamic therapy and immune adjuvant for antitumor immune responses. In Mn-mediated Fenton-like reaction, bicarbonate ( ...

    Yushuo Feng, Yaqing Liu, **aoqian Ma, Lihua Xu, Dandan Ding in Journal of Nanobiotechnology (2022)

  9. Article

    Open Access

    Carbonized paramagnetic complexes of Mn (II) as contrast agents for precise magnetic resonance imaging of sub-millimeter-sized orthotopic tumors

    Paramagnetic complexes containing gadolinium ions have been widely used for magnetic resonance imaging (MRI) in clinic. However, these paramagnetic complexes pose some safety concerns. There is still a demand ...

    Ruixue Qin, Shi Li, Yuwei Qiu, Yushuo Feng, Yaqing Liu in Nature Communications (2022)

  10. Article

    Open Access

    Minimally invasive separation surgery for the treatment of spinal metastases with small incision and freehand pedicle screw fixation: the surgical learning curve

    Minimally invasive separation surgery (MISS) is a safe and effective surgical technique, the current optimal treatment for spinal metastases. However, the learning curve for this technique has not been analyze...

    Jiaming Lin, **aojun Zhu, Qinglian Tang, **chang Lu in BMC Musculoskeletal Disorders (2022)

  11. No Access

    Article

    Restoration of dystrophin expression in mice by suppressing a nonsense mutation through the incorporation of unnatural amino acids

    Approximately 11% of monogenic diseases involve nonsense mutations that are caused by premature termination codons. These codons can in principle be read-through via the site-specific incorporation of unnatura...

    Ningning Shi, Qi Yang, Haoran Zhang, Jiaqi Lu in Nature Biomedical Engineering (2022)

  12. Article

    Open Access

    NIR-II emissive AIEgen photosensitizers enable ultrasensitive imaging-guided surgery and phototherapy to fully inhibit orthotopic hepatic tumors

    Accurate diagnosis and effective treatment of primary liver tumors are of great significance, and optical imaging has been widely employed in clinical imaging-guided surgery for liver tumors. The second near-i...

    Ruizhen Jia, Han Xu, Chenlu Wang, Lichao Su, **peng **g in Journal of Nanobiotechnology (2021)

  13. Article

    Open Access

    X-ray-charged bright persistent luminescence in NaYF4:Ln3+@NaYF4 nanoparticles for multidimensional optical information storage

    NaYF4:Ln3+, due to its outstanding upconversion characteristics, has become one of the most important luminescent nanomaterials in biological imaging, optical information storage, and anticounterfeiting applicati...

    Yixi Zhuang, Dunrong Chen, Wen**g Chen, Wenxing Zhang in Light: Science & Applications (2021)

  14. Article

    Open Access

    Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis

    Effectively activating macrophages against cancer is promising but challenging. In particular, cancer cells express CD47, a ‘don’t eat me’ signal that interacts with signal regulatory protein alpha (SIRPα) on ...

    Lang Rao, Lei Wu, Zhida Liu, Rui Tian, Guocan Yu, Zijian Zhou in Nature Communications (2020)

  15. No Access

    Article

    LiF@SiO2 nanocapsules for controlled lithium release and osteoarthritis treatment

    Electrolytes can be taken orally or intravenously as supplements or therapeutics. However, their therapeutic window may exceed the serum toxicity threshold, making systemic delivery a poor option. Local inject...

    Trever Todd, Zhenhui Lu, **min Zhao, Benjamin Cline, Weizhong Zhang in Nano Research (2018)

  16. No Access

    Article

    Rethinking cancer nanotheranostics

    Advances in nanoparticle synthesis and engineering have produced nanoscale agents affording both therapeutic and diagnostic functions that are often referred to by the portmanteau ‘nanotheranostics’. The field...

    Hongmin Chen, Weizhong Zhang, Guizhi Zhu, ** **e in Nature Reviews Materials (2017)

  17. No Access

    Chapter

    Sustainable Consumption and Production in China

    The rising problem of severe resource scarcity, environmental pollution and ecological degradation has become a great constraint on economic development in China. Sustainable consumption and production (SCP), as ...

    Hongmin Chen in Handbook on Sustainability Transition and Sustainable Peace (2016)

  18. No Access

    Article

    High precision landing site map** and rover localization for Chang’e-3 mission

    This paper presents the comprehensive results of landing site topographic map** and rover localization in Chang’e-3 mission. High-precision topographic products of the landing site with extremely high resolu...

    ZhaoQin Liu, KaiChang Di, Man Peng in Science China Physics, Mechanics & Astrono… (2015)

  19. Article

    The role of tumour-associated MUC1 in epithelial ovarian cancer metastasis and progression

    The most common ovarian cancer is epithelial ovarian cancer (EOC) characterised by few early symptoms, widespread peritoneal dissemination and ascites at advanced stages that result in poor prognosis. Despite ...

    Junli Deng, Li Wang, Hongmin Chen, Lei Li, Yiming Ma in Cancer and Metastasis Reviews (2013)

  20. No Access

    Article

    Co-expression of CD147/EMMPRIN with monocarboxylate transporters and multiple drug resistance proteins is associated with epithelial ovarian cancer progression

    Cancer metastasis and anti-cancer drug resistance are the major reason for the failure of clinical cancer treatment. We evaluated CD147, monocarboxylate transporters (MCT1 and MCT4), and multidrug resistance (...

    Hongmin Chen, Li Wang, Julia Beretov, **gli Hao in Clinical & Experimental Metastasis (2010)

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