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Article
Towards hydrometeorological thresholds of reservoir-induced landslide from subsurface strain observations
Synergistic multi-factor early warning of large-scale landslides is a crucial component of geohazard prevention and mitigation efforts in reservoir areas. Landslide forecasting and early warning based on surfa...
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Article
Temporal stacking of sub-pixel offset tracking for monitoring slow-moving landslides in vegetated terrain
Monitoring slow-moving landslides in densely vegetated areas using X-band Synthetic Aperture Radar (SAR) data posed challenges due to the dramatic loss of coherence during SAR interferometry and the relative l...
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Article
Open AccessCACA guidelines for holistic integrative management of adult acute myeloid leukemia
The CACA Guidelines was summarized by Hematology Oncology Committee of China Anti- Cancer Association. This portion of the CACA Guidelines for adult acute myeloid leukemia (AML) not only focuses on diagnosis, ...
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Article
Open AccessCellular hierarchy insights reveal leukemic stem-like cells and early death risk in acute promyelocytic leukemia
Acute promyelocytic leukemia (APL) represents a paradigm for targeted differentiation therapy, with a minority of patients experiencing treatment failure and even early death. We here report a comprehensive si...
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Article
Shear deformation calculation of landslide using distributed strain sensing technology considering the coupling effect
Deformation monitoring is of great significance in understanding the evolution process of landslides and evaluating their stability conditions. Distributed strain sensing (DSS) technology, with obvious advanta...
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Article
Targeting HDAC3 to overcome the resistance to ATRA or arsenic in acute promyelocytic leukemia through ubiquitination and degradation of PML-RARα
Acute promyelocytic leukemia (APL) is driven by the oncoprotein PML-RARα, which recruits corepressor complexes, including histone deacetylases (HDACs), to suppress cell differentiation and promote APL initiati...
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Article
Open AccessThe clinical impact of IKZF1 mutation in acute myeloid leukemia
Genetic heterogeneity poses a great challenge to the understanding and management of acute myeloid leukemia (AML). Knowledge of the IKZF1 mutation in AML specifically is extremely limited. In a previous work, we ...
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Article
Open AccessAMLnet, A deep-learning pipeline for the differential diagnosis of acute myeloid leukemia from bone marrow smears
Acute myeloid leukemia (AML) is a deadly hematological malignancy. Cellular morphology detection of bone marrow smears based on the French–American–British (FAB) classification system remains an essential crit...
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Article
Optimization of the digital image correlation method for deformation measurement of geomaterials
For the application of the digital image correlation (DIC) method in the deformation measurement of geomaterials, the conventional approaches can hardly realize optimized results in terms of precision and spee...
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Article
Exploring efficiency of biochar in enhancing water retention in soils with varying grain size distributions using ANN technique
Recently, incentives have been provided in many countries, including Canada and Denmark, to produce biochar for construction usage. This is done because biochar is carbon negative and can help achieve the emis...
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Article
Open AccessDistinct outcomes, ABL1 mutation profile, and transcriptome features between p190 and p210 transcripts in adult Philadelphia-positive acute lymphoblastic leukemia in the TKI era
The differential signaling and outcome of patients with p190 or p210 transcripts of BCR-ABL1 have been systematically investigated in chronic myeloid leukemia rather than in Philadelphia chromosome-positive ac...
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Article
Landslide displacement prediction based on a novel hybrid model and convolutional neural network considering time-varying factors
Accurate landslide displacement prediction is essential for an early warning system. At present, the inputs of the data-driven models adopted in landslide displacement prediction remain unchanged. However, con...
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Article
Open AccessFatal hemorrhagic pneumonia in patients with hematologic diseases and Stenotrophomonas maltophilia bacteremia: a retrospective study
Fatal hemorrhagic pneumonia is one of the most severe manifestations of Stenotrophomonas maltophilia (SM) infections. Here, we aimed to investigate the clinical characteristics of SM bacteremia and to identify...
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Article
Open AccessDFOS Applications to Geo-Engineering Monitoring
Optical fiber sensing technology has developed rapidly since the 1980s with the development of the optical fiber and fiber optical communication technology. It is a new type of sensing technology that uses lig...
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Article
Open AccessNot BCL2 mutation but dominant mutation conversation contributed to acquired venetoclax resistance in acute myeloid leukemia
Venetoclax (VEN) plus azacitidine has become the first-line therapy for elderly patients with acute myeloid leukemia (AML), and has a complete remission (CR) plus CR with incomplete recovery of hemogram rate o...
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Article
PSO-SVM-based deep displacement prediction of Majiagou landslide considering the deformation hysteresis effect
The accuracy of landslide displacement prediction can effectively prevent casualties and economic losses. To achieve accurate prediction of the Majiagou landslide displacement in the Three Gorges Reservoir (TG...
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Article
A machine learning method for inclinometer lateral deflection calculation based on distributed strain sensing technology
Due to its unique advantages, the distributed fiber optical sensing (DFOS) technology has been used to study the performance of inclinometer so as to monitor landslide deformation. Strain distribution of incli...
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Article
Soil strain-field and stability analysis of cut slope based on optical fiber measurement
A relatively small laboratory model of soil slope was constructed, and a special strain-sensing cable was embedded in the slope soil mass. The strain at different positions of the model slope was measured usin...
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Article
Development and application of a fixed-point fiber-optic sensing cable for ground fissure monitoring
Ground fissure is a serious geological disaster that may endanger the safety of surrounding people and infrastructures. In this paper, the distributed fiber-optic sensing (DFOS) technology is adopted to monito...
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Article
Monitoring and warning of landslides and debris flows using an optical fiber sensor technology
Landslides and debris flows are typical geo-hazards which occur in hilly or mountainous regions. Debris flows may result from landslides. Geotechnical instrumentation plays an important role in monitoring and ...
