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2,056 Result(s)
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Article
Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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Article
Experimental and DFT Investigations of AlNbTiVZr High Entropy Alloys with Excellent Mechanical Properties
This study investigated the microstructure and mechanical properties of AlNbTiVZr series high-entropy alloys (HEAs) through both experimental studies and density functional theory calculations. Significant imp...
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Nonlinear Dynamics of Giant Magnetostrictive Actuator Based on Fractional-Order Time-Lag Feedback Control
Investigating the nonlinear dynamic response of giant magnetostrictive actuator (GMA) is a valuable subject in the field of precision engineering. In order to effectively control the nonlinear dynamic response...
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Article
Open Access0.75% ropivacaine may be a suitable drug in pregnant women undergoing urgent cesarean delivery during labor analgesia period
3% chloroprocaine (CP) has been reported as the common local anesthetic used in pregnant women undergoing urgent cesarean delivery during labor analgesia period. However, 0.75% ropivacaine is considered a prom...
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Open AccessRedefined background state in the tropical Pacific resolves the entanglement between the background state and ENSO
Understanding the co-variability between the El Niño–Southern Oscillation (ENSO) and the background state in the tropical Pacific is critical for projecting future ENSO. The difficulty is rooted in a circular ...
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Article
Open AccessCorrection: Gut microbiota-derived propionate mediates the neuroprotective effect of osteocalcin in a mouse model of Parkinson’s disease
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Article
Tribo-dynamic modelling and analysis for a high-speed helical gear system with time-varying backlash and friction under Elastohydrodynamic Lubrication condition
High-speed gear reducers are highly sensitive to vibration and noise, especially in new-energy vehicles. Hence, the current nonlinear dynamics model of gears does not fully consider the influence of tooth micr...
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A genetic algorithm-optimized backpropagation neural network model for predicting soil moisture content using spectral data
Accurate assessment of soil moisture content (SMC) is crucial for applications in climate science, hydrology, ecology, and agriculture. However, conventional SMC characterization and measurement are expensive,...
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Article
Investigation of Al/CeO2 interfacial relationships for epitaxial growth of Al on CeO2 substrates: first-principles calculation
CeO2 has high elastic modulus and thermal stability, as well as good surface effects, making it ideal as a reinforcement for aluminum matrix composites. In this paper, the interfacial relationships between Al and...
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Open AccessGrowth characteristics of HCT116 xenografts lacking asparagine synthetase vary according to sex
Sex-related differences in colorectal (CRC) incidence and mortality are well-documented. However, the impact of sex on metabolic pathways that drive cancer growth is not well understood. High expression of asp...
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Article
Atomic insights for elevated modulus in Al–Li alloys: synergies and design strategy
Al–Li alloys, characterized by their lightweight and high strength, are essential structural materials in aerospace industry. Unraveling the atomic mechanisms that enhance the modulus of Al–Li alloys is key to...
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Article
Effect of induction heating composite shot peening on surface integrity parameters of 20CrMnTi gear steel
Shot peening is widely used to increase the fatigue strength of materials by inducing plastic deformation and introducing residual compressive stresses on the material surface. To enhance the effects of shot p...
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Article
Open AccessEmergent normal fluid in the superconducting ground state of overdoped cuprates
The microscopic mechanism for the disappearance of superconductivity in overdoped cuprates is still under heated debate. Here we use scanning tunneling spectroscopy to investigate the evolution of quasiparticl...
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Article
Open AccessCIC::NUTM1 sarcomas occurred in soft tissues of upper limbs : a rare case report and literature review
CIC-rearranged sarcomas (CRS) represent a new entity of undifferentiated small round cell sarcoma belonging to the Ewing-like sarcomas family. CRS are the most common type. Fusion partners for the CIC gene includ...
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Open AccessAssociations of life’s essential 8 with extent of multi-territorial atherosclerotic plaques and stenosis: a cross-sectional study
Life’s Essential 8 (LE8), the recently updated construct for quantifying cardiovascular health, is related to the risks of cardiovascular events. The present study aimed to evaluate associations of LE8 score w...
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PGK1 Is Involved in the HIF-1 Signaling Pathway as a Hub Gene for Ferroptosis After Traumatic Brain Injury
The pathogenesis of ferroptosis in traumatic brain injury (TBI) is unclear; therefore, we aimed to identify key molecules associated with ferroptosis in TBI using bioinformatics analysis to determine its under...
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Open AccessHigh-dimensional mediation analysis for continuous outcome with confounders using overlap weighting method in observational epigenetic study
Mediation analysis is a powerful tool to identify factors mediating the causal pathway of exposure to health outcomes. Mediation analysis has been extended to study a large number of potential mediators in hig...
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Article
Experimental Study on Towing Characteristics of Composite Bucket Wellhead Platform
With the rapid development of large-scale development of marginal oilfields in China, simple wellhead platforms that are simple in structure and easy to install have become an inevitable choice in the process ...
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Spatial and widely targeted metabolomics and anatomical analysis reveal the mechanisms associated with petal bicolor patterning of two Dendrobium species
Orchid flowers possess high ornamental value owing to their delicate structure and color. The color patterns are a result of unbalanced pigment distribution among the petal segments, with bicolor being the mos...
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An Efficient GIPM Algorithm for Computing the Smallest V-Singular Value of the Partially Symmetric Tensor
Real partially symmetric tensors arise from the strong ellipticity condition problem in solid mechanics and the entanglement problem in quantum physics. In this paper, we try to compute the smallest V-singular...