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Article
Open AccessPrevention of postoperative intrapericardial adhesion by dextrin hydrogel
Postoperative intrapericardial adhesion increases the risk of complications in patients undergoing reoperation. We investigated the effect of a bioabsorbable dextrin hydrogel (DHG) on the formation of intraper...
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Article
Open AccessIndomethacin reduces rates of aortic dissection and rupture of the abdominal aorta by inhibiting monocyte/macrophage accumulation in a murine model
Aortic dissection is a life-threatening condition, which is characterised by separation of the constituent layers of the aortic wall. We have recently shown that monocyte/macrophage infiltration into the aorti...
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Article
Open AccessPropagation-based phase-contrast synchrotron imaging of aortic dissection in mice: from individual elastic lamella to 3D analysis
In order to show the advantage and potential of propagation-based phase-contrast synchrotron imaging in vascular pathology research, we analyzed aortic medial ruptures in BAPN/AngII-infused mice, a mouse model...
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Chapter
Mouse Model of Abdominal Aortic Aneurysm Induced by CaCl2
Abdominal aortic aneurysm (AAA) is a common and fatal disease for which pathogenesis is still uncertain. Reproducible and standardized animal model of AAA is essential to obtain the knowledge of the molecular ...
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Chapter
Tissue Remodeling in Vascular Wall in Kawasaki Disease-Related Vasculitis Model Mice
Kawasaki disease is the most common acute systemic vasculitis of unknown etiology in children [1] and can cause inflammation of the coronary arteries leading to aneurysms. Tenascin-C, an extracellular matrix p...
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Article
Granulocyte macrophage colony-stimulating factor is required for aortic dissection/intramural haematoma
Aortic dissection and intramural haematoma comprise an aortopathy involving separation of the aortic wall. Underlying mechanisms of the condition remain unclear. Here we show that granulocyte macrophage colony...
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Article
Open AccessTenascin C protects aorta from acute dissection in mice
Acute aortic dissection (AAD) is caused by the disruption of intimomedial layer of the aortic walls, which is immediately life-threatening. Although recent studies indicate the importance of proinflammatory re...
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Chapter and Conference Paper
On Formal Series of Jacobi Forms and Borcherds Products
By Fourier-Jacobi expansion, a Siegel modular form of degree 2 gives a family of Jacobi forms of weight k and index ...
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Article
Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice
Lysyl oxidase (LOX) and LOX-like protein-1 (LOXL-1) are extracellular matrix-embedded amine oxidases that have critical roles in the cross-linking of collagen and elastin. LOX family proteins are abundantly ex...
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Article
Open AccessSex and age-level differences of walking time in preschool children on an obstacle frame
Step** over an obstacle is a kind of compound movement that makes walking more difficult, especially for preschool children. This study examines sex and age-level differences in walking time in preschool chi...
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Chapter and Conference Paper
Regression of Abdominal Aortic Aneurysms through Pharmacologic Therapy
Abdominal aortic aneurysm (AAA) is a common disease that eventually results in aortic rupture with high mortality. Although a pharmacologic therapy for AAA is eagerly awaited, the destruction of the aortic wal...
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Article
Turning back the clock: regression of abdominal aortic aneurysms via pharmacotherapy
Abdominal aortic aneurysm (AAA) is a common disease that causes progressive expansion and rupture of the aorta with high mortality. There is a large and unmet need for nonsurgical treatment for AAA. Research h...
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Article
Generalizations of Ho–Lee’s binomial interest rate model I: from one- to multi-factor
In this paper a multi-factor generalization of Ho–Lee model is proposed. In sharp contrast to the classical Ho–Lee, this generalization allows for those movements other than parallel shifts, while it still is ...
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Article
Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase
Abdominal aortic aneurysm (AAA) is a common disease among elderly people that, when surgical treatment is inapplicable, results in progressive expansion and rupture of the aorta with high mortality. Although n...
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Protocol
Gene Silencing Using Adenoviral RNAi Vector in Vascular Smooth Muscule Cells and Cardiomyocytes
RNA interference (RNAi) is a new and rapidly progressing technology for facilitating functional gene silencing. To perform highly efficient RNAi in cardiomyocytes, vascular smooth muscle cells, and vascular en...
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Article
The graded ring of hermitian modular forms of degree 2
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Article
Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro
During the development of hypertrophy, cardiac myocytes increase organization of the sarcomere, a highly ordered contractile unit in striated muscle cells. Several hypertrophic agonists, such as angiotensin II...
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Article
Calcineurin—the missing link in cardiac hypertrophy
Transgenic mice that overexpress calcineurin develop cardiac hypertrophy, which can be prevented by treatment with immunosuppressive drugs that inhibit calcineurin.