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Article
Open AccessA tripartite organelle platform links growth factor receptor signaling to mitochondrial metabolism
One open question in the biology of growth factor receptors is how a quantitative input (i.e., ligand concentration) is decoded by the cell to produce specific response(s). Here, we show that an EGFR endocytic...
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Article
Open AccessTissue fluidification promotes a cGAS–STING cytosolic DNA response in invasive breast cancer
The process in which locally confined epithelial malignancies progressively evolve into invasive cancers is often promoted by unjamming, a phase transition from a solid-like to a liquid-like state, which occur...
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Article
Open AccessAuthor Correction: Tissue fluidification promotes a cGAS–STING cytosolic DNA response in invasive breast cancer
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Article
Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control
The sympathetic system maintains a physiological balance, adjusts bodily functions during daily living activities, and can activate stress responses. The authors identify a variety of unique sympathetic neuron...
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Article
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
Based on single cell RNA-sequencing of 622 adult mouse sensory neurons, Usoskin et al. performed unbiased classification to identify the cellular and molecular complexity underlying somatic sensation. Eleven diff...
