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  1. Article

    Open Access

    Calorie restriction mimetic drugs could favorably influence gut microbiota leading to lifespan extension

    Calorie restriction (CR) can prolong human lifespan, but enforcing long-term CR is difficult. Thus, a drug that reproduces the effects of CR without CR is required. More than 10 drugs have been listed as CR mi...

    Tomoya Shintani, Hideya Shintani, Masashi Sato, Hisashi Ashida in GeroScience (2023)

  2. No Access

    Article

    Mutant firefly luciferases with improved specific activity and dATP discrimination constructed by yeast cell surface engineering

    Pyrosequencing system utilizing luciferase is one of the next-generation DNA sequencing systems. However, there is a crucial problem with the current pyrosequencing system: luciferase cannot discriminate betwe...

    Tatsuya Fushimi, Natsuko Miura, Hideya Shintani in Applied Microbiology and Biotechnology (2013)