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  1. Article

    Open Access

    Cryo-EM analysis of homodimeric full-length LRRK2 and LRRK1 protein complexes

    Leucine-rich repeat kinase 2 (LRRK2) is a large multidomain protein implicated in the pathogenesis of both familial and sporadic Parkinson’s disease (PD), and currently one of the most promising therapeutic ta...

    Kushal Sejwal, Mohamed Chami, Hervé Rémigy, Renée Vancraenenbroeck… in Scientific Reports (2017)

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    Article

    Probing the Influence of Mutations on the Stability of a Ferredoxin by Mass Spectrometry

    Hydrogen/deuterium exchange, which depends on solvent accessibility, can be probed by mass spectrometry (MS) to get information on protein conformation or protein–ligand interaction. In this work, the conforma...

    Hervé Rémigy, Michel Jaquinod, Yves Pétillot, Jean Gagnon… in Journal of Protein Chemistry (1997)