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Open AccessLevel and correlates of physical activity among children and adolescents with juvenile idiopathic arthritis compared to controls: results from a German nationwide prospective observational cohort study
Physical active lifestyles are essential throughout growth and maturation and may offer potential preventive and therapeutic benefit in patients with juvenile idiopathic arthritis (JIA). Insufficient physical ...
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When the Skin Turns Blue, Bleeds, and Then Turns Black
Vasculitic diseases are among the most complex autoimmune/autoinflammatory diseases. Attempts are made to approach the various manifestations in terms of the affection of different vessel sizes and the autoant...
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Is Every Early Childhood Polyarthritis with Uveitis also a JIA?
When the concepts of autoinflammatory diseases/fever syndromes were still unknown, there were always children in the cohorts of various rheumatology centers who were assigned to genuine rheumatic diseases, but...
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Immediate Hip Pain After Sports and Jum**
In pediatric and adolescent rheumatology, one is occasionally confronted with the question of whether the visible and measured inflammation actually corresponds to an immunological-rheumatological disease in t...
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When the Skin and Neck Stretch
In the context of connective tissue weakness and wound healing disorders, genetically caused structural connective tissue diseases such as Ehlers-Danlos or Marfan syndrome must be considered. However, benign h...
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From Nail Bed Inflammation Straight to the Wheelchair—and When the Newborn No Longer Moves Its Leg
Within the last decades, the clinical picture of a septic arthritis and also bacterial osteomyelitis has changed, among other things because the spectrum of pathogens has changed. If one assumes a highly inflamma...
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Worm-Like Movement, and the Tonsil was Inflamed
Within the last few decades, the frequency of rheumatic fever as a post-streptococcal disease has significantly decreased for reasons that remain unclear. The frequency of reactive arthritis and other possible di...
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When the Skin Just Won’t Heal
The spectrum of uncontrolled inflammatory reactions has significantly deepened in the understanding of the pathophysiology of autoimmune, autoinflammatory, and peri-/post-infectious diseases in recent years. I...
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When Every Movement and Even Laughter Becomes Agony
The clinical care of patients with muscular weakness/inflammation and concurrent skin changes in the form of dermatomyositis has seen significant advancements in the last decade. On one hand, overlap** phenomen...
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The Muscle Taut and Abdominal Pain
The Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS) is one of the genetically determined periodic fever syndromes, it is inherited in an autosomal dominant manner and is caused by various muta...
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When Sweating and Drafts Repeatedly Cause Fever
Urticaria triggered by cold and especially by cool drafts is a prominent anamnestic detail and in itself almost pathognomonic. It directly points to the autoinflammatory syndrome APLAID. This is an autoinflammato...
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When a Child’s Hip Hurts and It’s not Rheumatism
In the case of unilateral painful protection in infancy, which clinically and sonographically shows signs of arthritis, a Morbus Perthes should always be considered in the differential diagnosis. From a rheumatol...
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A Walk Like Charlie Chaplin
Clinically, the rare hypophosphatasia was traditionally assigned to endocrinology, although since the 1990s there has been increasing evidence for an inflammatory pathophysiology within this bone metabolism di...
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When the Skin Hardens and Calcifies
Both localized and systemic scleroderma are considered complex autoimmune diseases with induration of the skin, subcutis, and fascia, which can impair the function of internal organs through fibrosis over time...
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Telemedizin in der neonatologischen Erstversorgung
Das Perinatalzentrum in der Klinik für Kinder und Jugendmedizin des Vivantes Klinikum, Berlin, hat 2017 die postnatale videoassistierte Erstversorgung kritisch kranker Neugeborener in 2 ortsfernen assoziierten...
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Open AccessLong-term follow-up of children with chronic non-bacterial osteomyelitis—assessment of disease activity, risk factors, and outcome
Chronic non-bacterial osteomyelitis (CNO) is an autoinflammatory bone-disease of unknown origin. The National Pediatric Rheumatologic Database (NPRD) collects long-term data of children and adolescents with rh...
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Open AccessTreat-to-target strategies for the management of familial Mediterranean Fever in children
The objective of this initiative was to develop a treat-to-target (T2T) approach for the management of patients with Familial Mediterranean Fever (FMF), including the definition of a complex treatment target, ...
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Wenn die Haut partout nicht heilen will
Das Spektrum von unkontrollierten Entzündungsreaktionen hat sich in den letzten Jahren signifikant in der Kenntnis der Pathophysiologie von Autoimmunitäts-, Autoinflammations- und peri-/postinfektiösen Erkrank...
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Wurmartige Bewegung, und die Mandel war entzündet
Innerhalb der letzten Jahrzehnte ist aus noch ungeklärten Gründen die Häufigkeit des rheumatischen Fiebers als Streptokokken-Folgeerkrankung deutlich zurückgegangen. Auch die Häufigkeit von reaktiven Arthritiden ...
