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    Open Access

    Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E2, dual specificity phosphatase 1 and tristetraprolin

    In many different cell types, pro-inflammatory agonists induce the expression of cyclooxygenase 2 (COX-2), an enzyme that catalyzes rate-limiting steps in the conversion of arachidonic acid to a variety of lip...

    Tina Tang, Thomas E. Scambler, Tim Smallie, Helen E. Cunliffe in Scientific Reports (2017)