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  1. Article

    Open Access

    DPYSL5 is highly expressed in treatment-induced neuroendocrine prostate cancer and promotes lineage plasticity via EZH2/PRC2

    Treatment-induced neuroendocrine prostate cancer (t-NEPC) is a lethal subtype of castration-resistant prostate cancer resistant to androgen receptor (AR) inhibitors. Our study unveils that AR suppresses the ne...

    Roosa Kaarijärvi, Heidi Kaljunen, Lucia Nappi, Ladan Fazli… in Communications Biology (2024)

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    Article

    The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae

    Catechol oxidases (EC 1.10.3.1) catalyse the oxidation of o-diphenols to their corresponding o-quinones. These oxidases contain two copper ions (CuA and CuB) within the so-called coupled type 3 copper site as fou...

    Nina Hakulinen, Chiara Gasparetti… in JBIC Journal of Biological Inorganic Chemi… (2013)