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  1. Article

    Open Access

    Repurposing approach identifies pitavastatin as a potent azole chemosensitizing agent effective against azole-resistant Candida species

    The limited number of antifungals and the rising frequency of azole-resistant Candida species are growing challenges to human medicine. Drug repurposing signifies an appealing approach to enhance the activity of ...

    Hassan E. Eldesouky, Ehab A. Salama, **aoyan Li, Tony R. Hazbun… in Scientific Reports (2020)

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  2. Article

    Open Access

    Ospemifene displays broad-spectrum synergistic interactions with itraconazole through potent interference with fungal efflux activities

    Azole antifungals are vital therapeutic options for treating invasive mycotic infections. However, the emergence of azole-resistant isolates combined with limited therapeutic options presents a growing challen...

    Hassan E. Eldesouky, Ehab A. Salama, Tony R. Hazbun… in Scientific Reports (2020)

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  3. Article

    Open Access

    Identification of a Phenylthiazole Small Molecule with Dual Antifungal and Antibiofilm Activity Against Candida albicans and Candida auris

    Candida species are a leading source of healthcare infections globally. The limited number of antifungal drugs combined with the isolation of Candida species, namely C. albicans and C. auris, exhibiting resistanc...

    Haroon Mohammad, Hassan E. Eldesouky, Tony Hazbun… in Scientific Reports (2019)

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