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Chapter and Conference Paper
A Pilot Study on the Prosodic Factors Influencing Voice Attractiveness of AI Speech
This study investigates the attractiveness of AI-synthesized voice and its influencing factors from the perspective of speech prosody. Firstly, a comparative analysis, including MOS (Mean Opinion Score) listen...
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Article
Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis of the Blood Proteome
Novel, effective, and safe preventive therapy targets for AF are still needed. Circulating proteins with causal genetic evidence are promising candidates. We aimed to systematically screen circulating proteins...
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Article
Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy
Abdominal aortic aneurysm (AAA) is one of the leading causes of death in the developed world and is currently undertreated due to the complicated nature of the disease. Herein, we aimed to address the therapeu...
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Article
Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases
Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. Genome-wide association studies (GWAS) are powerful epidemiological tools to find genes and variants associated with cardiova...
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Article
Open AccessMEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk
A major challenge in genetic association studies is that most associated variants fall in the non-coding part of the human genome. We searched for variants associated with bone mineral density (BMD) after enri...
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Article
Open AccessLaminar Flow Attenuates Macrophage Migration Inhibitory Factor Expression in Endothelial Cells
Macrophage migration inhibitory factor (MIF) is a non-canonical cytokine that is involved in multiple inflammatory diseases, including atherosclerosis. High MIF expression found in leukocytes which facilitates...