-
Article
Open AccessPJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma
Chemoresistance is a main reason for treatment failure in patients with nasopharyngeal carcinoma, but the exact regulatory mechanism underlying chemoresistance in nasopharyngeal carcinoma remains to be elucida...
-
Article
Fine-tuning the structure-tolerance-antitumor efficacy axis of prodrug nanoassemblies via branched aliphatic functionalization
Small-molecule prodrug nanoassemblies have emerged as efficient antitumor drug delivery systems. However, in the case of camptothecins-based prodrug nanoassemblies, linear aliphatic side chain modification oft...
-
Article
Open AccessTranscription factor ATMIN facilitates chemoresistance in nasopharyngeal carcinoma
Despite that the docectaxel-cisplatin-5-fluorouracil (TPF) induction chemotherapy has greatly improved patients’ survival and became the first-line treatment for advanced nasopharyngeal carcinoma (NPC), not al...
-
Chapter and Conference Paper
Development of Sealing Joint for Collecting Slip Ring
The cable from the collecting slip ring is connected with the cable from the coiled tubing drum union, and the power supply from the surface to the downhole electric drilling tool and signal transmission are d...
-
Chapter and Conference Paper
Application of Direct Torque Control (DTC) in the Drilling System of Electric Drilling Tool
Drilling system with electric drilling tool is one of key drilling technologies for the development of electric-driven drilling in the days to come, but the characteristics of rock cutting by downhole electric...
-
Chapter and Conference Paper
Design and Test of Cable Sealing Component of Conductive Slip Ring for Electric Drilling System
The conductive slip ring is a key device for achieving underground power supply and bidirectional information transmission of Electric Drilling System, and the sealing of non-circular cross-section cables is a...
-
Article
Deepfake detection based on remote photoplethysmography
Deepfake, which superimpose an image of one person’s face on another person’s image. However, the number of malicious Deepfake uses is largely dominant. Deepfake technology has also improved in recent years, m...
-
Article
Open AccessPrivate banking development in China under two organizational structures: Economic analysis from an organizational innovation perspective
This paper investigates optimal decisions for private banking development in China under two innovative organizational structures—the big retail mode (BRM) and the independent development mode (IDM). Under the...
-
Article
Open AccessAxial superior facet slope may determine anterior or posterior atlantoaxial displacement secondary to os odontoideum and compensatory mechanisms of the atlantooccipital joint and subaxial cervical spine
To introduce novel parameters in determining directions of os odontoideum (OO) with atlantoaxial displacement (AAD) and compensations of cervical sagittal alignment after displacement.
-
Article
Enhancing global thinking can reduce the misconception of accumulation: A potential way to mitigate climate change
Climate change and global warming have long been attention and concern all over the world. However, there is always a debate about when and to what degree to take action like reducing carbon dioxide emissions....
-
Article
Open AccessTRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models
Although radiotherapy can promote antitumour immunity, the mechanisms underlying this phenomenon remain unclear. Here, we demonstrate that the expression of the E3 ubiquitin ligase, tumour cell-intrinsic tripa...
-
Article
Cross-modal retrieval with dual optimization
For the flexible retrieval of data in different modalities, cross-modal retrieval has gradually attracted the attention of researchers. However, there is a heterogeneity gap between the data of different modal...
-
Chapter and Conference Paper
Development of Intelligent Drill Pipe for Power Supply and Communication
Power supply and communication intelligent drill pipe is a bridge to realize high-speed two-way information communication and power transmission between ground and underground. In order to realize intelligent ...
-
Chapter and Conference Paper
Development of Balanced Torque Drilling Tools
Drilling of hard formations (especially interlayer) by PDC bits is frequented by severe stick slip and bit bouncing/jum**, and low ROP and short service life of PDC bit restrict the efficient development of ...
-
Article
Open AccessImmune-regulating strategy against rheumatoid arthritis by inducing tolerogenic dendritic cells with modified zinc peroxide nanoparticles
In hypoxic dendritic cells (DCs), a low level of Zn2+ can induce the activation of immunogenic DCs (igDCs), thereby triggering an active T-cell response to propel the immune progression of rheumatoid arthritis (R...
-
Article
Open AccessA lncRNA signature associated with tumor immune heterogeneity predicts distant metastasis in locoregionally advanced nasopharyngeal carcinoma
Increasing evidence has revealed the roles of long noncoding RNAs (lncRNAs) as tumor biomarkers. Here, we introduce an immune-associated nine-lncRNA signature for predicting distant metastasis in locoregionall...
-
Article
Forecasting US Stock Market Returns: A Japanese Candlestick Approach
A Japanese candlestick chart consists of not only the closing price but also the high, low and opening price information. Using the Japanese candlestick, this paper investigates the forecasting power of the sh...
-
Article
Detection and genetic characteristics of porcine bocavirus in central China
To investigate the epidemic profile and genetic diversity of porcine bocavirus (PBoV), 281 clinical samples, including 236 intestinal tissue samples and 45 fecal samples were collected from diarrheic piglets o...
-
Chapter and Conference Paper
A Cross-Modal Image-Text Retrieval System with Deep Learning
With the generation of massive data, cross-modal image and text retrieval has attracted more and more attention. However, there is a heterogeneity gap between the data of different modalities, which cannot be ...
-
Chapter and Conference Paper
Exploring People’s Hue Ranking Ability Across the Color Ring: Taking the Categorization Effect into Consideration
HCI specialists are fully aware that effective use of color can enhance interaction design. Therefore a precise map** between colors’ physical attributes and human perception is needed. Whereas the CIELch co...
