314 Result(s)
-
Article
Open AccessManagement and treatment of severe immune-related hepatotoxicity based on clinical and pathological characteristics
The management of severe immune-related hepatotoxicity (irH) needs to be further optimized. This study aims to analyze the clinical characteristics of severe irH; improve the therapeutic strategy, especially s...
-
Article
Open AccessEffect of esketamine combined with dexmedetomidine on delirium in sedation for mechanically ventilated ICU patients: protocol for a nested substudy within a randomized controlled trial
Use of sedatives and analgesics is associated with the occurrence of delirium in critically ill patients receiving mechanical ventilation. Dexmedetomidine reduces the occurrence of delirium but may cause hypot...
-
Article
Animal Models of Chronic Migraine: From the Bench to Therapy
Chronic migraine is a disabling progressive disorder without effective management approaches. Animal models have been developed and used in chronic migraine research. However, there are several problems with e...
-
Article
Open AccessDevelopment and validation of a risk prediction model for invasiveness of pure ground-glass nodules based on a systematic review and meta-analysis
Assessing the aggressiveness of pure ground glass nodules early on significantly aids in making informed clinical decisions.
-
Article
Open AccessIncidence and treatment-related risk factors of inhibitor development after intensive FVIII replacement for major orthopaedic surgery in previous treated haemophilia A
Haemophilia A (HA) is an X-linked recessive bleeding disorder caused by lack or deficiency of coagulation factor VIII.
-
Article
Pulsatile Tinnitus: Differential Diagnosis and Approach to Management
The purpose of this review is to provide an updated approach to the evaluation and management of pulsatile tinnitus (PT), an uncommon but often treatable subtype of tinnitus.
-
Article
Sino-German symposium on total-body PET/CT in theranostics
-
Article
Open AccessGardening and subjective cognitive decline: a cross-sectional study and mediation analyses of 136,748 adults aged 45+ years
Given the benefits of gardening for physical and psychological health, we explored whether gardening was associated with lower risks of subjective cognitive decline (SCD), a precursor of dementia, and SCD-rela...
-
Article
Endoscopic endonasal resection of symptomatic Rathke’s cleft cysts: outcomes of the strategy to maintain the fenestration open
Purpose: The study intends to clarify the optimal endoscopic endonasal surgical strategy for symptomatic Rathke’s cleft cysts (RCCs). Methods: We retrospectively analyzed patients with RCCs that underwent EEA ...
-
Article
Open AccessA new notable compression source of left renal vein entrapment: right renal artery
To estimate the incidences of left renal vein (LRV) entrapment by right renal artery (RRA), a phenomenon primarily reported as case reports.
-
Article
Rapid advancements in PET/MR: the 4th chinese PET/MR academic symposium
-
Article
Open AccessVulnerable conditions syndemic, depression, and suicidal ideation among school children in China: cross-sectional census findings
Mental health issues (depression and suicidal ideation) are increasingly common in children and emerge as escalating public health concerns. The syndemics that underline the importance of risk factor clusterin...
-
Article
Open AccessMolecular subtypes of clear cell renal carcinoma based on PCD-related long non-coding RNAs expression: insights into the underlying mechanisms and therapeutic strategies
PCD-related long non-coding RNAs (PRLs) are rarely investigated in relation to clear cell renal carcinoma (ccRCC). As part of this study, we evaluated the immunological potential of PRL signatures as a biomark...
-
Article
Open AccessCombination of betulinic acid and EGFR-TKIs exerts synergistic anti-tumor effects against wild-type EGFR NSCLC by inducing autophagy-related cell death via EGFR signaling pathway
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of lung cancer patients with mutated EGFR. However, the efficacy of EGFR-TKIs in wild-type EGFR tumor...
-
Article
Cancer progression and tumor hypercoagulability: a platelet perspective
Venous thromboembolism, which is common in cancer patients and accompanies or even precedes malignant tumors, is known as cancer-related thrombosis and is an important cause of cancer- associated death. At pre...
-
Article
Open AccessDo nutritional assessment tools (PNI, CONUT, GNRI) predict adverse events after spinal surgeries? A systematic review and meta-analysis
Nutritional assessment tools are used to predict outcomes in cancer. However, their utility in patients undergoing spinal surgery is unclear. This review examined if prognostic nutritional index (PNI), control...
-
Article
Open AccessThe learning curve for minimally invasive Achilles repair using the “lumbar puncture needle and oval forceps” technique
An acute Achilles tendon rupture represents a common tendon injury, and its operative methods have been developed over the years. This study aimed to quantify the learning curve for the minimally invasive acut...
-
Article
Open AccessEndoscopic submucosal dissection versus surgery for T1b esophageal carcinoma: a single-center retrospective study
Endoscopic submucosal dissection (ESD) is a preferred treatment option for superficial esophageal squamous cell carcinoma (SESCC). However, only few studies compared long-term survival outcomes of ESD with sur...
-
Article
Targeting STING elicits GSDMD-dependent pyroptosis and boosts anti-tumor immunity in renal cell carcinoma
While Stimulator-of-interferon genes (STING) is an innate immune adapter cruicial for sensing cytosolic DNA and modulating immune microenvironment, its tumor-promoting role in tumor survival and immune evasion...
-
Article
Protein Supplements with Short Peptides Are Better than Complex Protein-Based Supplements on Improving Early Fat-Free Mass Loss Following Bariatric Surgery: A Retrospective Cohort Study
Bariatric surgery (BS) patients are advised to consume protein supplements to prevent fat-free mass (FFM) loss. However, limited research has explored the efficacy of diverse protein presentations on FFM prese...
