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  1. Article

    Open Access

    Neutrophil degranulation and myocardial infarction

    Myocardial infarction (MI) is one of the most common cardiac emergencies with high morbidity and is a leading cause of death worldwide. Since MI could develop into a life-threatening emergency and could also s...

    Nan Zhang, **ahenazi Aiyasiding, Wen-**g Li… in Cell Communication and Signaling (2022)

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  2. Article

    Open Access

    Alternative autophagy: mechanisms and roles in different diseases

    As an important mechanism to maintain cellular homeostasis, autophagy exerts critical functions via degrading misfolded proteins and damaged organelles. Recent years, alternative autophagy, a new type of autop...

    Hong Feng, Nian Wang, Nan Zhang, Hai-han Liao in Cell Communication and Signaling (2022)

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  3. No Access

    Article

    Bcl6 Suppresses Cardiac Fibroblast Activation and Function via Directly Binding to Smad4

    Bcl6, a critical pro-oncogene of human B-cell lymphomas, can promote tumor progress. Previous studies have found that Bcl6 participates in hypoxia injury in cardiomyocytes. However, the effect of Bcl6 on cardi...

    Jian Ni, Qing-qing Wu, Hai-han Liao, Di Fan, Qi-zhu Tang in Current Medical Science (2019)

  4. No Access

    Article

    AdipoRon, an adiponectin receptor agonist, attenuates cardiac remodeling induced by pressure overload

    AdipoRon, a small-molecule adiponectin receptor (AdipoR) agonist, has been reported to be implicated in cardiovascular diseases. However, its role in pressure-overload-induced cardiac remodeling is still elusi...

    Ning Zhang, Wen-Ying Wei, Hai-Han Liao, Zheng Yang, Can Hu… in Journal of Molecular Medicine (2018)

  5. No Access

    Article

    Sanguinarine Attenuates Lipopolysaccharide-induced Inflammation and Apoptosis by Inhibiting the TLR4/NF-κB Pathway in H9c2 Cardiomyocytes

    The inflammatory response is involved in the pathogenesis of the most common types of heart disease. Sanguinarine (SAN) has various pharmacological properties such as anti-inflammatory, antioxidant, antibacter...

    Yan-yan Meng, Yuan Liu, Zhe-fu Hu, Yao Zhang, Jian Ni… in Current Medical Science (2018)

  6. Article

    CTRP3 attenuates cardiac dysfunction, inflammation, oxidative stress and cell death in diabetic cardiomyopathy in rats

    Oxidative stress, inflammation and cell death are closely involved in the development of diabetic cardiomyopathy (DCM). C1q/tumour necrosis factor-related protein-3 (CTRP3) has anti-inflammatory properties but...

    Zhen-Guo Ma, Yu-Pei Yuan, Si-Chi Xu, Wen-Ying Wei, Chun-Ru Xu, **n Zhang… in Diabetologia (2017)

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  7. No Access

    Article

    Apigenin alleviates STZ-induced diabetic cardiomyopathy

    Apigenin is an important component of fruits and vegetables in human daily diets. Several cellular and animal models have been performed to demonstrate its anti-oxidant and anti-inflammatory bioactivities. How...

    Huang-Jun Liu, Yun-Lin Fan, Hai-Han Liao, Yuan Liu… in Molecular and Cellular Biochemistry (2017)

  8. No Access

    Article

    Oleanolic acid alleviated pressure overload-induced cardiac remodeling

    Previous study has demonstrated that oleanolic acid (OA) possessing the anti-inflammatory and anti-oxidant properties blunted high-glucose-induced diabetic cardiomyopathy and ameliorated experimental autoimmun...

    Hai-Han Liao, Nan Zhang, Hong Feng, Ning Zhang… in Molecular and Cellular Biochemistry (2015)