3 Result(s)
within
Hai-bo Zhu
Internal Medicine
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Article
IMM-H007 attenuates isoprenaline-induced cardiac fibrosis through targeting TGFβ1 signaling pathway
Upon chronic stress, β-adrenergic receptor activation induces cardiac fibrosis and leads to heart failure. The small molecule compound IMM-H007 has demonstrated protective effects in cardiovascular diseases vi...
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Article
Protective effects of octacosanol on 6-hydroxydopamine-induced Parkinsonism in rats via regulation of ProNGF and NGF signaling
To investigate the protective effects of octacosanol in 6-hydroxydopamine-induced Parkinsonian rats and find whether octacosanol has effects on pro nerve growth factor (pro-NGF), NGF and the downstream effecto...
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Article
A cell-based model of α-synucleinopathy for screening compounds with therapeutic potential of Parkinson's disease
To develop a cell-based model by stable transfection of SH-SY5Y with mutant A53T human α-synuclein, recapitulating neurotoxicity of α-synuclein overexpression.
