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  1. Article

    Numerical simulation of microstructure and microporosity morphology in directional solidification of aluminum-copper alloys: Effect of copper content and withdrawal rate

    Microporosity formed in the solidification process of Al alloys is detrimental to the alloy properties. A two-dimensional cellular automaton (CA) model was developed to simulate the microstructure and micropor...

    Wei Yuan, Hai-dong Zhao, Xu Shen, Chun Zou, Yuan Liu, Qing-yan Xu in China Foundry (2024)

  2. Article

    Open Access

    Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway

    Hyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is ...

    Hai-Hua Liu, Wei Wei, Fei-Fei Wu, Lu Cao, Bing-Jie Yang in BMC Cardiovascular Disorders (2024)

  3. Article

    Open Access

    Exploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)

    Bilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic properties. The systemic immune-inflammation index (SII) is a recent marker tha...

    Shan-Shan Huang, Yi Ding, **ao-Na Yi, Hai-Yan Mao in European Journal of Medical Research (2024)

  4. Article

    Open Access

    Safety of embryo cryopreservation: insights from mid-term placental transcriptional changes

    In recent years, with benefits from the continuous improvement of clinical technology and the advantage of fertility preservation, the application of embryo cryopreservation has been growing rapidly worldwide....

    Qin-Yu Luo, Si-Wei Zhang, Hai-Yan Wu, Jia-Ying Mo in Reproductive Biology and Endocrinology (2024)

  5. No Access

    Article

    Machine Learning Approach in Dosage Individualization of Isoniazid for Tuberculosis

    Isoniazid is a first-line antituberculosis agent with high variability, which would profit from individualized dosing. Concentrations of isoniazid at 2 h (C2h), as an indicator of safety and efficacy, are importa...

    Bo-Hao Tang, **n-Fang Zhang, Shu-Meng Fu, Bu-Fan Yao in Clinical Pharmacokinetics (2024)

  6. No Access

    Article

    Clinical characteristics of membranous nephropathy after allogeneic hematopoietic stem cell transplantation: A real-world multicenter study

    Membranous nephropathy (MN) is a rare complication that can occur after allogeneic hematopoietic stem cell transplantation (allo-HSCT). MN patients may develop nephrotic syndrome or even kidney failure, which ...

    Yue **, Peng Zhao, Yuan-Yuan Zhang, Yi-Shan Ye, Fang Zhou in Annals of Hematology (2024)

  7. Article

    Correction to: Process Optimization and Influencing Factors of Supersonic High-Energy Plasma Spraying of Al2O3-PF Composite Coatings on Polymer Matrix Composite Surface

    Ming Liu, Qi-qing Peng, Yan-fei Huang, Guo-zheng Ma in Journal of Thermal Spray Technology (2024)

  8. Article

    Open Access

    Combined detection of serum EFNA1 and MMP13 as diagnostic biomarker for gastric cancer

    We previously identified that serum EFNA1 and MMP13 were potential biomarker for early detection of esophageal squamous cell carcinoma. In this study, our aim is to explore the diagnostic value of serum EFNA1 ...

    Ling-Yu Chu, Fang-Cai Wu, Hai-Peng Guo, Jian-Jun **e, Qi-Qi Qu in Scientific Reports (2024)

  9. Article

    Open Access

    Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury

    Glutamate is traditionally viewed as the first messenger to activate NMDAR (N-methyl-d-aspartate receptor)-dependent cell death pathways in stroke1,2, but unsuccessful clinical trials with NMDAR antagonists impli...

    Ke Lai, Iva Pritišanac, Zhen-Qi Liu, Han-Wei Liu, Li-Na Gong, Ming-**an Li in Nature (2024)

  10. No Access

    Article

    Response strategies of leaf vein traits and stomatal traits of Aegiceras corniculatum to shrimp aquaculture wastewater discharge

    Sediments, waters and vegetation work together and cooperate mutually to maintain normal function of mangrove wetland ecosystem. To gained a comprehensive understanding of the response strategies existed by th...

    Ying-Ying Qin, Ge-Ge Zhu, Ming-Zhong Liang, Hai-Lei Zheng, Jun-Wei Li in Aquatic Ecology (2024)

  11. No Access

    Article

    A low-melting-point metal do** strategy for the synthesis of small-sized intermetallic Pt5Ce fuel cell catalysts

    Carbon-supported platinum-lanthanum (Pt-Ln) intermetallic compound (IMC) nanoparticles with high activity and robust stability have been demonstrated as promising cathode catalysts for proton-exchange membrane...

    Zi-Jun Zou, Shi-Yi Yin, Yao Tang, Sheng-Liang Zhong, Lei Wang, Shi-Long Xu in Nano Research (2024)

  12. No Access

    Article

    Research progress and development tendency on storage mechanism of multi-principal element alloys for hydrogen/tritium storage

    Sustainable clean energy is gradually replacing traditional fossil energy sources in important industrial applications and is placing higher demands on the technologies of energy storage and transportation. Th...

    Yi-Jie Chen, Jian-Wei Zhang, Can-Hui Xu, Mu-Hong Li, Shuang-Lin Hu in Rare Metals (2024)

  13. No Access

    Article

    Overexpression of the MiAGL1 gene from mango promoted flowering in transgenic Arabidopsis

    MADS-box genes play a vital role in the vegetative and reproductive growth of plants. In this study, a MiAGL1 gene was cloned and identified from mango (Mangifera indica L.). The DNA sequence of AGAMOUS-LIKE1 (Mi...

    Xue-mei Zeng, **n-hua He, Wen-**g Mo in Journal of Plant Biochemistry and Biotechn… (2024)

  14. Article

    Correction to: AHA Life’s Essential 8 and new‑onset CKD: a prospective cohort study from the UK Biobank

    Yong-**ang Ruan, Mao-**ong Wu, **g-Wei Gao in Clinical and Experimental Nephrology (2024)

  15. No Access

    Article

    Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction

    Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...

    **u-xiu Wang, Yi-ming Zhao, Qian-yun Zhang, **g-xuan Zhao in Acta Pharmacologica Sinica (2024)

  16. No Access

    Article

    In situ synthesis of porous Pt–Pd bimetallic structures for sweat glucose biosensing using dynamic hydrogen bubble template method

    Yi-Wen Guo, Qian-Hui Wei, Fei Wei, Hao Liu, Hong-Bin Zhao, Dong Wang in Rare Metals (2024)

  17. No Access

    Article

    Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience

    Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...

    Rui Ma, Dan-** Zhu, **ao-Hui Zhang, Lan-** Xu, Yu Wang in Bone Marrow Transplantation (2024)

  18. No Access

    Article

    Geochemical Characterization and Paleoclimatic Significance of the **aganchaigou Formation–**ayoushashan Formation in the Youquanzi Area, Qaidam Basin

    Since the Cenozoic, the Earth’s climate has experienced significant transformations, transitioning from a “greenhouse” to the current “icehouse,” where ice sheets presently cover both Antarctica and the Arctic...

    Zheng Yong-Sheng, Yi Hai-Sheng, Song Wei, Wu Kun-Yu, Yang Yun in Doklady Earth Sciences (2024)

  19. No Access

    Article

    Association Between Preeclampsia and Blood Pressure in Offspring: A Systematic Review and Meta-Analysis

    Pregnancy-induced preeclampsia is a severe pregnancy complication and preeclampsia has been associated with an increased risk of chronic hypertension for offspring. However, the magnitude of the overall effect...

    Min Xu, Hai-**a Wang, ** Zu, Nan Jiang, **g-Feng Bian in Current Hypertension Reports (2024)

  20. No Access

    Article

    Potential Plausible Role of Stem Cell for Treating Depressive Disorder: a Retrospective Review

    Depression poses a significant threat to global physical and mental health, impacting around 3.8% of the population with a rising incidence. Current treatment options primarily involve medication and psycholog...

    Zhuo Chang, Qing-yi Wang, Lu-hao Li, Bei Jiang, Xue-ming Zhou in Molecular Neurobiology (2024)

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