2,392 Result(s)
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Numerical simulation of microstructure and microporosity morphology in directional solidification of aluminum-copper alloys: Effect of copper content and withdrawal rate
Microporosity formed in the solidification process of Al alloys is detrimental to the alloy properties. A two-dimensional cellular automaton (CA) model was developed to simulate the microstructure and micropor...
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Open AccessSodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway
Hyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is ...
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Open AccessExploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)
Bilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic properties. The systemic immune-inflammation index (SII) is a recent marker tha...
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Open AccessSafety of embryo cryopreservation: insights from mid-term placental transcriptional changes
In recent years, with benefits from the continuous improvement of clinical technology and the advantage of fertility preservation, the application of embryo cryopreservation has been growing rapidly worldwide....
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Machine Learning Approach in Dosage Individualization of Isoniazid for Tuberculosis
Isoniazid is a first-line antituberculosis agent with high variability, which would profit from individualized dosing. Concentrations of isoniazid at 2 h (C2h), as an indicator of safety and efficacy, are importa...
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Clinical characteristics of membranous nephropathy after allogeneic hematopoietic stem cell transplantation: A real-world multicenter study
Membranous nephropathy (MN) is a rare complication that can occur after allogeneic hematopoietic stem cell transplantation (allo-HSCT). MN patients may develop nephrotic syndrome or even kidney failure, which ...
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Correction to: Process Optimization and Influencing Factors of Supersonic High-Energy Plasma Spraying of Al2O3-PF Composite Coatings on Polymer Matrix Composite Surface
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Open AccessCombined detection of serum EFNA1 and MMP13 as diagnostic biomarker for gastric cancer
We previously identified that serum EFNA1 and MMP13 were potential biomarker for early detection of esophageal squamous cell carcinoma. In this study, our aim is to explore the diagnostic value of serum EFNA1 ...
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Open AccessGlutamate acts on acid-sensing ion channels to worsen ischaemic brain injury
Glutamate is traditionally viewed as the first messenger to activate NMDAR (N-methyl-d-aspartate receptor)-dependent cell death pathways in stroke1,2, but unsuccessful clinical trials with NMDAR antagonists impli...
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Response strategies of leaf vein traits and stomatal traits of Aegiceras corniculatum to shrimp aquaculture wastewater discharge
Sediments, waters and vegetation work together and cooperate mutually to maintain normal function of mangrove wetland ecosystem. To gained a comprehensive understanding of the response strategies existed by th...
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A low-melting-point metal do** strategy for the synthesis of small-sized intermetallic Pt5Ce fuel cell catalysts
Carbon-supported platinum-lanthanum (Pt-Ln) intermetallic compound (IMC) nanoparticles with high activity and robust stability have been demonstrated as promising cathode catalysts for proton-exchange membrane...
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Research progress and development tendency on storage mechanism of multi-principal element alloys for hydrogen/tritium storage
Sustainable clean energy is gradually replacing traditional fossil energy sources in important industrial applications and is placing higher demands on the technologies of energy storage and transportation. Th...
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Article
Overexpression of the MiAGL1 gene from mango promoted flowering in transgenic Arabidopsis
MADS-box genes play a vital role in the vegetative and reproductive growth of plants. In this study, a MiAGL1 gene was cloned and identified from mango (Mangifera indica L.). The DNA sequence of AGAMOUS-LIKE1 (Mi...
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Correction to: AHA Life’s Essential 8 and new‑onset CKD: a prospective cohort study from the UK Biobank
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Acetylcytidine modification of Amotl1 by N-acetyltransferase 10 contributes to cardiac fibrotic expansion in mice after myocardial infarction
Cardiac fibrosis is a pathological scarring process that impairs cardiac function. N-acetyltransferase 10 (Nat10) is recently identified as the key enzyme for the N4-acetylcytidine (ac4C) modification of mRNAs...
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In situ synthesis of porous Pt–Pd bimetallic structures for sweat glucose biosensing using dynamic hydrogen bubble template method
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Salvage haploidentical transplantation for graft failure after first haploidentical allogeneic stem cell transplantation: an updated experience
Graft failure is a fatal complication following allogeneic stem cell transplantation where a second transplantation is usually required for salvage. However, there are no recommended regimens for second transp...
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Geochemical Characterization and Paleoclimatic Significance of the **aganchaigou Formation–**ayoushashan Formation in the Youquanzi Area, Qaidam Basin
Since the Cenozoic, the Earth’s climate has experienced significant transformations, transitioning from a “greenhouse” to the current “icehouse,” where ice sheets presently cover both Antarctica and the Arctic...
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Association Between Preeclampsia and Blood Pressure in Offspring: A Systematic Review and Meta-Analysis
Pregnancy-induced preeclampsia is a severe pregnancy complication and preeclampsia has been associated with an increased risk of chronic hypertension for offspring. However, the magnitude of the overall effect...
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Potential Plausible Role of Stem Cell for Treating Depressive Disorder: a Retrospective Review
Depression poses a significant threat to global physical and mental health, impacting around 3.8% of the population with a rising incidence. Current treatment options primarily involve medication and psycholog...