-
Article
Potential Plausible Role of Stem Cell for Treating Depressive Disorder: a Retrospective Review
Depression poses a significant threat to global physical and mental health, impacting around 3.8% of the population with a rising incidence. Current treatment options primarily involve medication and psycholog...
-
Article
Open AccessTemporal changes in cyclinD-CDK4/CDK6 and cyclinE-CDK2 pathways: implications for the mechanism of deficient decidualization in an immune-based mouse model of unexplained recurrent spontaneous abortion
Deficient endometrial decidualization has been associated with URSA. However, the underlying mechanism is poorly understood. This study aimed to investigate the temporal cytokine changes and the involvement of...
-
Article
Open AccessGenetic aetiology of primary adrenal insufficiency in Chinese children
Primary adrenal insufficiency (PAI) is life-threatening, and a definitive aetiological diagnosis is essential for management and prognostication. We conducted this study to investigate the genetic aetiologies ...
-
Article
Open Access4.1 Probing Arterial Stiffness at the Nano-Scale using the Internal Mammary Artery as a Novel Target
Arterial stiffening is associated with structural and biomechanical alterations in the aorta. However, there are still gaps in our understanding as to how the structure and properties of arteries across the va...
-
Article
Open AccessNovel aggrecan variant, p. Gln2364Pro, causes severe familial nonsyndromic adult short stature and poor growth hormone response in Chinese children
Mutations in the aggrecan (ACAN) gene can cause short stature (with heterogeneous clinical phenotypes), impaired bone maturation, and large variations in response to growth hormone (GH) treatment. For such cases,...
-
Article
Open AccessP136: Altered Adventitial Collagen Fibril Mechanics and Morphology with High Pulse Wave Velocity
Arterial stiffening, occurring as part of the natural aging process of the artery, is well- established as a powerful predictor of cardiovascular disease. However, little is known about how localised changes i...
-
Article
Open AccessP1.2 Nanomechanical Alterations in the Adventitial Layer of the Internal Mammary Artery of Patients with High Pwv
Arterial stiffening occurs as part of the natural ageing process, and is thought to be related to the accumulation of collagen and degradation of elastin. However, little is known about how regional variations...
-
Article
Synthesis of ratiometric fluorescent nanoparticles for sensing oxygen
A facile reprecipitation-encapsulation method is used for the preparation of ratiometric fluorescent nanoparticles (NPs) for sensing intracellular oxygen. The surface of the NPs is modified in-situ with poly-L...
-
Chapter and Conference Paper
Online Algorithm for 1-Space Bounded Multi-dimensional Bin Packing
In this paper, we study 1-space bounded multi-dimensional bin packing. A sequence of items arrive over time, each item is a d-dimensional hyperbox and the length of each side is no more than 1. These items must b...
-
Chapter and Conference Paper
Online Uniformly Inserting Points on Grid
In this paper, we consider the problem of inserting points in a square grid, which has many background applications, including halftone in reprographic and image processing. We consider an online version of th...
