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    Article

    Preparation of methoxy poly(ethyleneglycol)-block-poly(caprolactone) via activated monomer mechanism and examination of micellar characterization

    The polymerization of ε–caprolactone (CL) in the presence of HCl·Et2O via activated monomer mechanism was performed to synthesize diblock copolymers composed of methoxy polyethyleneglycol (MPEG) and poly(ε–caprol...

    Moon Suk Kim, Hoon Hyun, Young Ho Cho, Kwang Su Seo, Woo Young Jang in Polymer Bulletin (2005)

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    Article

    Chondrogenic differentiation of bone marrow stromal cells in transforming growth factor-β1 loaded alginate bead

    We developed alginate beads loaded with transforming growth factor-β1 (TGF-β1) to examine the possible application of the scaffold and cytokine carrier in tissue engineering. In this study, bone marrow stromal ce...

    Ki Suk Park, Chae Moon **, Soon Hee Kim, John M. Rhee in Macromolecular Research (2005)

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    Article

    Surface and chemical properties of surface-modified UHMWPE powder and mechanical and thermal properties of its impregnated PMMA bone cement V. Effect of silane coupling agent on the surface modification of UHMWPE powder

    Conventional poly(methyl methacrylate)(PMMA) bone cement has been widely used as an useful biopolymeric material to fix bone using artificial prostheses. However, many patients had to be reoperated, due to the...

    Dae Hyeok Yang, Goan Hee Yoon, Gyun Jeong Shin, Soon Hee Kim in Macromolecular Research (2005)

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    Article

    The effect of gamma irradiation on PLGA and release behavior of BCNU from PLGA wafer

    The objectives of this study were to investigate the influence of gamma irradiation for sterilization on poly(D,L-lactide-co-glycolide) (PLGA) with different molecular weight and the effect of gamma irradiation o...

    ** Soo Lee, Gang Soo Chae, Gilson Khang, Moon Suk Kim in Macromolecular Research (2003)

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    Article

    Controlled release of nerve growth factor from sandwiched poly(L-lactide-co-glycolide) films for the application in neural tissue engineering

    In order to fabricate new sustained delivery device of nerve growth factor (NGF), we developed NGFloaded biodegradable poly(L-lactide-co-glycolide) (PLGA, the mole ratio of lactide to glycolide 75∶25, molecular w...

    Gilson Khang, Eun Kyung Jeon, John M. Rhee, Ilwoo Lee in Macromolecular Research (2003)

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    Article

    Local drug delivery system using biodegradable polymers

    For last five years, we are develo** the novel local drug delivery devices using biodegradable polymers, especially polylactide (PLA) and poly(D,L-lactide-co-glycolide) (PLGA) due to its relatively good biocomp...

    Gilson Khang, John M. Rhee, Je Kyo Jeong, Jeong Sik Lee in Macromolecular Research (2003)

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    Article

    Preparation of 5-fluorouracil-loaded poly(L-lactide-co-glycolide) wafer and evaluation ofin vitro release behavior

    The controlled delivery of anticancer agents using biodegradable polymeric implant has been developed to solve the problem of penetration of blood brain barrier and severe systemic toxicity. This study was per...

    ** Soo Lee, Gang Soo Chae, Tae Kun An, Gilson Khang in Macromolecular Research (2003)

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    Article

    Evaluation ofin vitro release profiles of fentanyl-loaded PLGA oligomer microspheres

    In order to the development of the delivery device of long-acting local anesthetics for postoperative analgesia and control of chronic pain of cancer patient, fentanyl-loaded poly(l-lactide-co-glycolide)|(PLGA, m...

    Gilson Khang, Sun-Ah Seo, Hak Soo Choi, John M. Rhee in Macromolecular Research (2002)

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    Article

    Preparation and characterization of small intestine submucosa powder impregnated poly(L-lactide) scaffolds: the application for tissue engineered bone and cartilage

    In order to endow with new bioactive functionality from small intestine submucosa (SIS) powder as natural source to poly(L-lactide) (PLA) and poly(lactide-co-glycolide) (PLGA) synthetic biodegradable polymer, por...

    Gilson Khang, John M. Rhee, Philkyung Shin, In Young Kim in Macromolecular Research (2002)

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    Article

    Effect of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) surface with different wettability on fibroblast behavior

    Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) is a microbial storage polymer with biodegradable properties. In order to improve the cell compatibility of PHBV surfaces, the physicochemical treatments have b...

    Sang ** Lee, Young Moo Lee, Gilson Khang, In Young Kim in Macromolecular Research (2002)

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    Chapter

    Cell Behavior on Polymer Surfaces with Different Functional Groups

    Recently a large number of research groups have studied the interaction of biomedical materials with cultured cells because cell-compatible materials are thought to be very important to many biomedical applica...

    ** Ho Lee, ** Whan Lee, Gilson Khang in Science and Technology of Polymers and Adv… (1998)

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    Chapter and Conference Paper

    Cell Adhesion and Protein Adsorption on Gradient Surfaces

    A new method for preparing a wettability gradient on polymer surfaces was developed. Low density polyethylene sheets were treated in air with corona from a knife-type electrode whose power gradually increases ...

    Hai Bang Lee, ** Ho Lee in Progress in Pacific Polymer Science 3 (1994)