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  1. No Access

    Article

    Ultrastructural and histochemical characterization of marmoset (Callithrix jacchus) Leydig cells during postnatal development

    Leydig cell development was investigated in the marmoset (Callithrix jacchus) testis from 24 h post partum (pp) up to sexual maturity, using ultrastructural and histochemical methods.

    G. M. Rune, Ph. de Souza, H. J. Merker in Anatomy and Embryology (1991)

  2. No Access

    Article

    The basement membrane of the persisting maternal blood vessels in the placenta of Callithrix jacchus

    Formation and morphology of the thickened basement membrane-like layer around the persisting maternal vessels of the Callithrix jacchus placenta were investigated from day 45 until term (day 142) using light, ...

    H. -J. Merker, D. Bremer, H. -J. Barrach, R. Gossrau in Anatomy and Embryology (1987)

  3. No Access

    Chapter and Conference Paper

    Production and Formation of the Basal Lamina

    The chemical composition of the basal lamina (BL), its morphology, localization and behaviour under experimental and pathological conditions have been investigated extensively over the last few years (Hawkes a...

    H.-J. Merker in Mesenchymal-Epithelial Interactions in Neural Development (1987)

  4. No Access

    Chapter and Conference Paper

    Cell-Matrix Interaction in the Differentiation of the Intestinal Epithelium

    Epithelio-mesenchymal interactions are a prerequisite for the normal cytodifferentiation of all epithelial tissues during ontogenesis. Whereas the pioneering investigators reported on the necessity of the mere...

    Ursula Hahn, D. Schuppan, E. G. Hahn… in Mesenchymal-Epithelial Interactions in Neu… (1987)

  5. No Access

    Article

    The effect of d-penicillamine of the skeletal development of rat foetuses

    Rats received 20, 50 or 100mg/animal d-penicillamine i. p. twice daily on days 15, 16, 17, 18 and 19 of gestation, i. e. a total dose of 200, 500 resp. 1000 mg/animal. At all dosages the number of fetal resorptio...

    H. J. Merker, L. Franke, Th. Günther in Naunyn-Schmiedeberg's Archives of Pharmacology (1975)

  6. No Access

    Article

    Benzo(a)pyrene hydroxylase activity in the whole implantation site, decidua, placenta and fetal membranes of the rat

    Treatment of pregnant rats with 40 mg benzo(a)pyrene (BP) per kg body weight p.o. 24 h prior to sacrifice results in an induction of BP hydroxylase activity in the whole implantation site, the decidua, the pla...

    Eva Schlede, H. -J. Merker in Naunyn-Schmiedeberg's Archives of Pharmacology (1974)

  7. No Access

    Article

    Effect of cyclophosphamide pretreatment of pregnant animals on the activity of nuclear DNA-dependent RNA-polymerases in different parts of rat embryos

    On day 13+0 h of gestation rats received 10 mg/kg cyclophosphamide i.p. 3, 9, and 24 h after administration of the drug the activities of the DNA-dependent RNA polymerase reactions were measured in the whole e...

    E. Köhler, H.-J. Merker in Naunyn-Schmiedeberg's Archives of Pharmacology (1973)

  8. No Access

    Article

    Growth kinetics of mammalian embryos during the stage of differentiation

    In order to get insight into the synthesis rates occuring in mammalian embryos during the phase of differentiation, wet and dry weight as well as DNA-, RNA-, and nitrogen content of the whole implantation site...

    E. Köhler, H. -J. Merker, W. Ehmke… in Naunyn-Schmiedeberg's Archives of Pharmaco… (1972)

  9. No Access

    Article

    Effect of benzo(α)pyrene treatment on the benzo(α)pyrene hydroxylase activity in maternal liver, placenta, and fetus of the rat during day 13 to day 18 of gestation

    Pregnant rats were treated with an oral dose of 40.0 mg benzo(α) pyrene (BP) per kg body weight and were sacrificed 24 h later. Maternal liver, placenta, and fetus were assayed for BP-hydroxylase activity. The...

    Eva Schlede, H.-J. Merker in Naunyn-Schmiedeberg's Archives of Pharmacology (1972)

  10. No Access

    Article

    Studies on the teratogenic phase specificity of actinomycin D in the rat

    In order to elucidate the phase specificity of the embryo-lethal and teratogenic action of actinomycin D (day 5–10 of gestation) rats received 3H-actinomycin D at different times of gestation. The distribution of...

    E. Köhler, H. -J. Merker in Naunyn-Schmiedeberg's Archives of Pharmacology (1972)

  11. No Access

    Article

    Biochemical studies on the nucleic acid metabolism of embryonic tissue and the effect of drugs

    D. Neubert, E. Oberdisse, H.-J. Merker… in Naunyn-Schmiedebergs Archiv für Pharmakolo… (1968)