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Article
Die seltene Fehlbildung der Nasenaplasie
Nach der Vorstellung eines Geschwisterpaares mit der seltenen angeborenen Form von Arrhinie wird ein aktueller Überblick über dieses Krankheitsbild gegeben sowie ein Erklärungsversuch zur Pathogenese unternomm...
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Article
Redifferentiation of dedifferentiated human chondrocytes in high-density cultures
High-density cultures are widely used as an in vitro model for studies of embryonic cartilage formation. In the present study we investigated the suitability of high-density cultures for the redifferentiation...
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Article
Elektronenmikroskopische Untersuchungen des menschlichen vomeronasalen Organs
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Article
Quinolone-induced arthropathy: exposure of magnesium-deficient aged rats or immature rats, mineral concentrations in target tissues and pharmacokinetics
Quinolone treatment or magnesium deficiency induce identical cartilage lesions in juvenile rats and show additive arthropathogenic effects. It has been shown previously that neither condition is arthropathoge...
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Article
Effects of Magnesium Deficiency on Magnesium and Calcium Content in Bone and Cartilage in Develo** Rats in Correlation to Chondrotoxicity
Quinolone-induced arthropathy has been described in juvenile rats between 3 and 6 weeks of age, but not in adult rats. The mechanism of this chondrotoxic effect is probably related to the Mg2+-chelating properti...
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Article
Electron microscopic and immunomorphological investigations on the mucosa of the human paranasal sinuses
The morphology of the mucosa from the human paranasal sinuses was investigated by electron microscopy. A total of 27 specimens was taken from 11 patients following midfacial fractures. All tissue samples were ...
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Article
Vergleichende Stabilitätsprüfungen von DHS- und γ-Nagel-Osteosynthesen bei instabilen pertrochantären Femurosteotomien
In 24 human cadaver femora standardized instable pertrochanteric osteotomies were created. The right and left femur of each pair were alternately selected for osteosyntheses with the gamma nail and the dynamic...
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Article
Intracellular collagen-like material in mouse embryonic mesenchymal cells incubated with TNF-α and IL-1β in organoid culture
Blastemal cells of embryonic mouse limb buds (day 12) were cultivated in organoid cultures in the presence of the human recombinant cytokines interleukin-1β (IL-1β) and tumour necrosis factor α (TNF-α). The ef...
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Article
Integrins on joint cartilage chondrocytes and alterations by ofloxacin or magnesium deficiency in immature rats
Recently, we showed that magnesium deficiency induces lesions in knee joint cartilage from 5-week-old rats that are very similar to ofloxacin-induced cartilage defects. We concluded that quinolone-induced art...
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Chapter and Conference Paper
Histomorphologische Analyse zu Anisotropie, Absorptions- und Streuungsverhalten operationsrelevanter Mittelohrstrukturen und der Eustachischen Röhre
Zur minimal-invasiven Chirurgie pathologischer Veränderungen des menschlichen Schalleitungsapparates und der durch die Mikroendoskopie ermöglichten Chirurgie obstruktiver Veränderungen innerhalb der Eustachisc...
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Chapter and Conference Paper
Elektronenoptische und immunfluoreszenzmikroskopische Untersuchungen der Basalmembran bei Erkrankungen der Stimmlippen
Die Basalmembran (BM) stellt eine extrazelluläre Struktur dar, die u.a. Epithelzellen vom Propriabindegewebe trennt. Lichtmikroskopisch einschichtig, bereits 1857 von Todd beschrieben, erscheint die BM im Elek...
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Chapter and Conference Paper
Das Vorkommen von intraepithelialen Leukozyten im Epithel der Nasenschleimhaut und der Stimmlippen
Schon seit langem sind Leukozyten im Epithel beschrieben worden, ein spezieller Mukosa-Typ wurde von Bonneville (1988), Goodman und Lefrancois (1989) und Guy-Grand (1991) im Ärodigestivtrakt beobachtet. Ähnlic...
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Article
Electron and fluorescence microscopic investigations on composition and structure of the epithelial basement membrane of the human inferior nasal concha
Light and electron microscopic as well as immunohistochemical investigations were performed on the basement membrane (BM) of the nasal mucosa from the inferior nasal conchae of 20 patients, aged 15–50 years. T...
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Article
Cell shape and arrangement of cultured aortic smooth muscle cells grown on collagen gels
Aortic smooth muscle cells (SMC) grown on conventional plastic culture dishes have morphological and functional properties of dedifferentiated cells in sub-culture. We examined the influence of collagen gels o...
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Article
Localization of collagen type VI in articular cartilage of young and adult mice
Collagen type VI was demonstrated immunomorphologically in articular cartilage (distal femur) of young (2–8 weeks) and adult mice by fluorescence and electron microscopy (gold-labelled second antibody—sandwich...
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Chapter and Conference Paper
Anatomie
Das Flimmerepithel, die seromukösen Drüsen und die verschiedenen Gefäße in den Nasenmuscheln des Menschen dienen zur Aufbereitung (Reinigung, Erwärmung und Befeuchtung) der Luft für die tiefen Atemwege. Trotz ...
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Article
Extracellular matrix in the rat spiral limbus
The matrix of the spiral limbus is obviously a special form of the intercellular substance. In the present study, the rat's spiral limbus was investigated by electron microscopy after fixation with ruthenium r...
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Article
Intercellular communication between cultured granulosa cells of the marmoset (Callithrix jacchus)
The influence of follicle-stimulating hormone, forskolin, insulin-like growth factor type I, epidermal growth factor, and 12-tetradecanoyl-phorbol-13-acetate on marmoset granulosa cell communication via gap ju...
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Article
Development of the basal lamina in xenografted human carcinomas: an ultrastructural and immunohistochemical study
The development of the basal lamina (BL), the key structure of the basement membrane (BM), was investigated in three xenografted human carcinomas of the sigmoid colon (CA 1), the lung (L 261), and the hypophar...
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Article
Ultrastructural and histochemical characterization of marmoset (Callithrix jacchus) Leydig cells during postnatal development
Leydig cell development was investigated in the marmoset (Callithrix jacchus) testis from 24 h post partum (pp) up to sexual maturity, using ultrastructural and histochemical methods.
