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  1. No Access

    Article

    Supplementation with Magnesium and Tocopherol Diminishes Quinolone-Induced Chondrotoxicity in Immature Rats

    Prof. Dr R. Stahlmann, R. Schwabe, K. Pfister, E. Lozo, M. Shakibaei, J. Vormann in Drugs (1999)

  2. No Access

    Article

    Quinolone-induced arthropathy: exposure of magnesium-deficient aged rats or immature rats, mineral concentrations in target tissues and pharmacokinetics

    Quinolone treatment or magnesium deficiency induce identical cartilage lesions in juvenile rats and show additive arthropathogenic effects. It has been shown previously that neither condition is arthropathoge...

    C. Förster, R. Schwabe, E. Lozo, U. Zippel, J. Vormann… in Archives of Toxicology (1997)

  3. No Access

    Article

    Effects of Magnesium Deficiency on Magnesium and Calcium Content in Bone and Cartilage in Develo** Rats in Correlation to Chondrotoxicity

    Quinolone-induced arthropathy has been described in juvenile rats between 3 and 6 weeks of age, but not in adult rats. The mechanism of this chondrotoxic effect is probably related to the Mg2+-chelating properti...

    J. Vormann, C. Förster, U. Zippel, E. Lozo, T. Günther… in Calcified Tissue International (1997)