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Open AccessImprovement of gemcitabine sensitivity of p53-mutated pancreatic cancer MiaPaCa-2 cells by RUNX2 depletion-mediated augmentation of TAp73-dependent cell death
Pancreatic cancer exhibits the worst prognostic outcome among human cancers. Recently, we have described that depletion of RUNX2 enhances gemcitabine (GEM) sensitivity of p53-deficient pancreatic cancer AsPC-1 ce...
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Article
Open AccessSilencing of RUNX2 enhances gemcitabine sensitivity of p53-deficient human pancreatic cancer AsPC-1 cells through the stimulation of TAp63-mediated cell death
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Article
Open AccessSilencing of RUNX2 enhances gemcitabine sensitivity of p53-deficient human pancreatic cancer AsPC-1 cells through the stimulation of TAp63-mediated cell death
Runt-related transcription factor 2 (RUNX2) has been considered to be one of master regulators for osteoblast differentiation and bone formation. Recently, we have described that RUNX2 attenuates p53/TAp73-dep...
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Article
Congenital Pulmonary–Systemic Collateral Vein without Obstructed Left Atrial Egress Is Associated with Conotruncal Anomalies
We present a case of congenital pulmonary systemic collateral vein associated with truncus arteriosus. Pulmonary systemic collateral vein with nonobstructed left atrial egress is different from those with obst...
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Article
Identification of early-responsive genes associated with the hypersensitive response to tobacco mosaic virus and characterization of a WRKY-type transcription factor in tobacco plants
In order to identify genes that are involved in the defense reaction against pathogen attack, we screened for examples that are regulated during the hypersensitive response (HR) to infection by tobacco mosaic...
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Article
Analysis of twisted nematic liquid crystal Fabry–Perot interferometer (TN-FPI) filter based on the coupled mode theory
The tuning characteristics of a twisted nematic (TN) liquid crystal (LC) Fabry–Perot interferometer (FPI) wavelength filter, which is a basic component of wavelength division multiplexed transmission systems, ...
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Article
Analysis of polarization-insensitive tunable optical filter using liquid crystal: connection formula and apparent paradox
The resonance characteristics of a twisted-nematic liquid crystal Fabry-Pe´rot wavelength filter (TN-FP) is analysed and it is shown that it obeys some simple laws hitherto unknown. A method to calculate the t...
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Article
Blood flow velocities in the cerebral arteries and descending aorta in small-for-dates infants
Resistive indices (RI) in the anterior cerebral artery (ACA), basilar artery (BA), middle cerebral artery (MCA) and descending aorta (DA) were obtained in 15 small-for-dates (SFD) infants who were, growth reta...
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Article
A case of Dandy-Walker malformation associated with occipital meningocele, microphthalamia, and cleft palate
We present a case of Dandy-Walker malformation associated with occipital meningocele, microphthalmia, and cleft palate. Small numbers of cases of Dandy-Walker malformation with occipital meningocele have been ...