222 Result(s)

Article

The absolute frequency reference unit for the spaceborne methane-sensing lidar mission MERLIN

Lidar systems have become an important technology in a variety of industrial and scientific applications. For terrestrial applications, such systems have been developed over the last decade and are commerciall...

D. Heinecke, T. Liebherr, D. Battles, K. Schleisiek, D. Fehrenbacher… in CEAS Space Journal (2019)

Article

Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells

Malignant tumors, such as colorectal cancer (CRC), are heterogeneous diseases characterized by distinct metabolic phenotypes. These include Warburg- and reverse Warburg phenotypes depending on differential dis...

K Diehl, L-A Dinges, O Helm, N Ammar, D Plundrich, A Arlt, C Röcken, S Sebens… in Oncogene (2018)

Chapter and Conference Paper

Future Perspectives for MBR Applications at the Erftverband

The river water association Erftverband looks back on two decades of experience in Membrane bioreactor (MBR) operations in the Erft river catchment in Germany. MBR operations have been monitored scientifically...

C. Brepols, K. Drensla, A. Janot, L. Beyerle… in Frontiers in Wastewater Treatment and Mode… (2017)

Chapter and Conference Paper

Improved Biological Nutrient Removal and Reduced Energy Consumption at a Retrofitted Wastewater Treatment Plant

A case-study of a retrofit of an existing wastewater treatment plant with full biological nutrient removal is described. During the planning process dynamic modelling was used, to evaluate effluent quality and...

C. Brepols, T. Engels, H. Schäfer in Frontiers in Wastewater Treatment and Modelling (2017)

Chapter

Das Rating der Nachhaltigkeit von Staaten – Analyse und Bewertung existierender Ratingmethoden

Der Beitrag beschäftigt sich mit der Analyse und Bewertung von Ratings, welche die Nachhaltigkeitsperformance von Staaten nach Environmental-, Social- und Governance (ESG)-Kriterien messen. Es wird das Ergebni...

H. Schäfer, F. Sauter in CSR und Finanzratings (2016)

Article

Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity

Evidence accumulates that the transcription factor nuclear factor E2-related factor 2 (Nrf2) has an essential role in cancer development and chemoresistance, thus pointing to its potential as an anticancer tar...

A Arlt, S Sebens, S Krebs, C Geismann, M Grossmann, M-L Kruse, S Schreiber… in Oncogene (2013)

Article

TGF-β1-dependent L1CAM expression has an essential role in macrophage-induced apoptosis resistance and cell migration of human intestinal epithelial cells

Patients with chronic inflammatory bowel disease (IBD) have an increased risk to develop colorectal cancer (CRC) particularly after long duration of the disease. Chronic inflammation of the intestinal mucosa i...

H Schäfer, B Struck, E-M Feldmann, F Bergmann, E Grage-Griebenow, C Geismann… in Oncogene (2013)

Article

Ultrafast transient generation of spin-density-wave order in the normal state of BaFe₂As₂ driven by coherent lattice vibrations

Ultrafast and intense optical pulses have been used to study spin-density-waves in pnictide compounds, which are known to exhibit unconventional superconductivity. The results show that the magnetic order foll...

K. W. Kim, A. Pashkin, H. Schäfer, M. Beyer, M. Porer, T. Wolf… in Nature Materials (2012)

Article

No evidence for association between a functional promoter variant of the Norepinephrine Transporter gene SLC6A2 and ADHD in a family-based sample

Noradrenergic neurotransmission influences executive functions, attentional performance, and general alertness, involving neuronal networks affected in attention deficit/hyperactivity disorder (ADHD). The nore...

T. J. Renner, T. T. Nguyen, M. Romanos… in ADHD Attention Deficit and Hyperactivity D… (2011)

Article

Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree

Attention-deficit/hyperactivity disorder (ADHD) is a common, highly heritable neurodevelopmental syndrome characterized by hyperactivity, inattention and increased impulsivity. To detect micro-deletions and mi...

K-P Lesch, S Selch, T J Renner, C Jacob, T T Nguyen, T Hahn… in Molecular Psychiatry (2011)

Article

L1CAM–integrin interaction induces constitutive NF-κB activation in pancreatic adenocarcinoma cells by enhancing IL-1β expression

L1 cell adhesion molecule (L1CAM) overexpression is often associated with bad prognosis in various human carcinomas. Recent studies also suggest a role of L1CAM in pancreatic ductal adenocarcinomas (PDAC). To ...

H Kiefel, S Bondong, N Erbe-Hoffmann, J Hazin, S Riedle, J Wolf, M Pfeifer… in Oncogene (2010)

Article

Serum metabolome analysis by ¹H-NMR reveals differences between chronic lymphocytic leukaemia molecular subgroups

Chronic lymphocytic leukaemia (CLL) is a heterogeneous disease exhibiting variable clinical course and survival rates. Mutational status of the immunoglobulin heavy chain variable regions (IGHVs) of CLL cells ...

D A MacIntyre, B Jiménez, E Jantus Lewintre, C Reinoso Martín, H Schäfer… in Leukemia (2010)

Article

Investigation of KYF₄: Yb, Er // KYF₄ nanocrystals — mechanism of the KYF₄ formation

H. Schäfer, P. Ptacek, K. Hickmann, M. Prinz… in Russian Journal of Inorganic Chemistry (2009)

Article

Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)

An elevated proteasome activity contributes to tumorigenesis, particularly by providing cancer cells with antiapoptotic protection and efficient clearance from irregular proteins. Still, the underlying mechani...

A Arlt, I Bauer, C Schafmayer, J Tepel, S Sebens Müerköster, M Brosch, C Röder… in Oncogene (2009)

Article

Isolation of microsatellite markers in the Emys orbicularis complex and development of multiplex PCR amplification

We report the development of 15 new microsatellite markers for Emys orbicularis and Emys trinacris. A survey of 20 individuals showed that all loci are highly polymorphic with 3–14 alleles per locus. Additionally...

I. Pedall, H. Schäfer, U. Fritz, M. Wink in Conservation Genetics (2009)

Article

Schmerzlose zervikale Raumforderung eines Jugendlichen

Dr. H. Kutta, H. Schäfer, A. Münscher, S. Wenzel in HNO (2008)

Article

Genome-wide linkage analysis of ADHD using high-density SNP arrays: novel loci at 5q13.1 and 14q12

Previous genome-wide linkage studies applied the affected sib-pair design; one investigated extended pedigrees of a genetic isolate. Here, results of a genome-wide high-density linkage scan of attention-defici...

M Romanos, C Freitag, C Jacob, D W Craig, A Dempfle, T T Nguyen… in Molecular Psychiatry (2008)