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  1. Article

    Microcirculation and intravascular coagulopathy in patients with severe sepsis and septic shock

    R Wimmer, S Franz, S Siebelist, M Uschner, C Seidelmann, H Ebelt… in Critical Care (2010)

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  2. Chapter

    Schock

    U. Müller-Werdan, M. Buerke, A. Christoph, R.R. Flieger… in Klinische Kardiologie (2006)

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    Article

    Zytokine: Klassifikation, Rezeptoren, Wirkungsmechanismen

    H. Loppnow in Der Internist (2001)

  4. Article

    Proinflammatory impact of norepinephrine in cardiomyocytes: increased interleukin-6 production, which is suppressed by carvedilol

    U Müller-Werdan, J Jacoby, H Loppnow, K Werdan in Critical Care (2000)

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  5. Article

    sCD14, IL-6 and TNF-receptors, but not IL-1, IL-8 or TNF-α are elevated in plasma of patients undergoing high risk coronary angioplasty with cardiopulmonary support

    R Prondzinsky, A Knüpfer, I Stabenow, F Redling, D Lehmann, J Radke… in Critical Care (2000)

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  6. Article

    Cardiopulmonary bypass contributes to less than half of interleukin-6 release post cardiac surgery

    R Prondzinsky, A Knüpfer, I Stabenow, F Redling, D Lehmann, J Radke… in Critical Care (2000)

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    Article

    Die akute septische Kardiomyopathie

    Damage/dysfunctioning of the heart forms part of the multiple organ dysfunction syndrome (MODS) in sepsis and SIRS. This acute septic cardiomyopathy is often underestimated in degree and relevance, although a...

    U. Müller-Werdan, C. Kuhn, K. Heinroth… in Intensivmedizin und Notfallmedizin (1997)

  8. Article

    Cellular mechanisms of acute septic cardiomyopathy: cardiodepressive profiles of endotoxin, tumor necrosis factor α and interleukin-1 in the cardiomyocyte

    U Müller-Werdan, H Schumann, H Loppnow, F Schlegel, S Koch, R Fuchs… in Critical Care (1997)

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  9. No Access

    Chapter

    Bacterial Endotoxin: Chemical Constitution, Biological Recognition, Host Response, and Immunological Detoxification

    The discovery of endotoxin dates from the late nineteenth century when Richard Pfeiffer, then working in Berlin, characterized endotoxins as heat-stable and cell-associated molecules (Westphal et al. 1977), thus ...

    E. T. Rietschel, H. Brade, O. Holst, L. Brade… in Pathology of Septic Shock (1996)

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    Article

    Specific binding of bacillus Calmette-Guérin to urothelial tumor cells in vitro

    Intravesical immunotherapy with bacillus Calmette-Guérin (BCG) against recurrences of superficial bladder cancer and carcinoma in situ is a highly effective regimen in urology. Despite intensive efforts to cla...

    B. Schneider, A. Thanhäuser, D. Jocham, H. Loppnow, E. Vollmer… in World Journal of Urology (1994)

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    Chapter

    The Active Principle of Bacterial Lipopolysaccharides (Endotoxins) for Cytokine Induction

    Toxic agents in bacterial cultures have been discov ered in the last decades of the nineteenth century. Pfeiffer described endotoxic in addition to exotoxic activities (Pfeiffer 1892), which include fever (Cen...

    H. Loppnow, H.-D. Flad, E. T. Rietschel… in Pathophysiology of Shock, Sepsis, and Orga… (1993)

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    Chapter and Conference Paper

    Molecular Aspects of the Chemistry and Biology of Endotoxin

    Endotoxins are integral constituents of the outer membrane of gram-negative bacteria such as the Enterobacteriaceae, Neisseriaceae, and Chlamydiaceae (Lüderitz et al. 1982). They participate in various physiol...

    E. Th. Rietschel, T. Kirikae, W. Feist, H. Loppnow… in Molecular Aspects of Inflammation (1991)

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    Chapter

    Lipid A, the Immunostimulatory Principle of Lipopolysaccharides ?

    Lipopolysaccharide (LPS) is an inducer of toxic and immunostimulatory or immunoregulatory responses (2). The lipid A moiety was shown to be the endotoxic principle of LPS (3, 9). Data about immunostimulatory p...

    H. Loppnow, I. Dürrbaum, H. Brade, C. A. Dinarello, S. Kusumoto… in Endotoxin (1990)

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    Article

    Die Adsorption von Sulfanilsäure, Sulfanilamid und Sulfaäthylthiodiazol an Plasmaeiweiß und ihr Einfluß auf Verteilungsvorgänge

    Es wurde in Dialysemodellversuchen mit Sulfanilsäure (I), Sulfanilamid (II) und Sulfaäthylthiodiazol (III) unter Bedingungen, die die Verhältnisse bei der in vivo-Verteilung hinsichtlich Eiweißgehalt in Blut, ...

    H. Langecker, H. Loppnow in Naunyn-Schmiedebergs Archiv für experiment… (1955)