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Article
Management of urinary calculi using endourology and extracorporeal shock wave lithotripsy (ESWL)
Childhood urolithiasis is uncommon, comprising 2% – 3% of urinary calculi. This paper presents our initial experience in the endourological (EU) treatment of 23 children with urinary calculi presenting to the ...
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Article
Laparoscopic pyloromyotomy for infantile hypertrophic pyloric stenosis
Although great advances in laparoscopic techniques have been made in the field of adult surgery, its application in infants and young children has been limited. We present a technique of laparoscopic pyloromyo...
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Article
Laparoscopic ovariopexy for paediatric pelvic malignancies
Ovariopexy can prevent radiation damage to the ovaries in children undergoing pelvic irradiation, and should be considered prior to radical curative radiotherapy. We report two children who have had successful...
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Article
Initial experience with laparoscopic adhesiolysis in children
Intra-abdominal adhesions are a well-known complication of laparotomy. We report our initial experience of ten children undergoing laparoscopy for the diagnosis and treatment of intra-abdominal adhesions. Sign...
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Article
Laparoscopic bipolar strip-tease appendicectomy
Since its conception, several techniques have been described for laparoscopic appendicectomy. We describe a technique which utilizes a 5-mm bipolar forceps designed to coagulate and cut tissues at the same tim...
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Article
Letter to the editor
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Article
Ectopic pancreatic rests: a rare cause of persistent umbilical discharge
Ectopic pancreatic rests are rare. We report two cases discovered in infants who underwent surgical exploration of the umbilicus for persistent umbilical discharge with peri-umbilical excoriation. A shallow s...
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Article
Laparoscopic resection of type I choledochal cyst
Type I choledochal cyst is a rare saccular or fusiform congenital dilatation of the extrahepatic biliary tract. It is usually treated by laparotomy at which the cyst is completely excised and a Roux-en-Y hepat...
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Article
The successful medical management of severe duodenal strictures secondary to eosinophilic gastroenteritis in an infant
Eosinophilic gastroenteritis is an uncommon condition of unknown etiology that has only been relatively recently reported. Its clinical manifestations range from a mild disease to more severe forms resembling ...
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Article
Assessment of Stem Cell Markers During Long-Term Culture of Mouse Embryonic Stem Cells
Embryonic stem (ES) cells have been in the fore front of scientific literature lately as having the potential for regeneration of many tissue types. Two important issues that need to be addressed are the cultu...
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Article
Lymphatic sparing, laparoscopic varicocelectomy: a new surgical technique
Several surgical options are available for managing varicoceles. Although conventional surgery offers good surgical results, the most common long-term complication of surgery is the development of hydroceles, ...
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Article
The Receptor Activator of Nuclear Factor-κB Ligand Inhibitor Osteoprotegerin Is a Bone-Protective Agent in a Rat Model of Chronic Renal Insufficiency and Hyperparathyroidism
Osteoprotegerin (OPG) acts by neutralizing the receptor activator of nuclear factor-κB ligand (RANKL), the primary mediator of osteoclast differentiation, function, and survival. We examined whether OPG could ...
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Article
Laparoscopic surgery in children is associated with an intraoperative hypermetabolic response
Laparoscopic surgery is thought to be associated with a reduced metabolic response compared to open surgery. Oxygen consumption ( ...
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Chapter and Conference Paper
Relative contribution of heart regions to the precordial ECG-an inverse computational approach
With an inverse computational approach using a multi-lead ECG recording of normal sinus rhythm in a patient spread of activation and repolarization was computed. Using this timing information, contributions to...
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Chapter and Conference Paper
Non-invasive imaging of activation times during drug inducedconduction changes
The feasibility was studied of monitoring changes in the activation sequence of the heart on the basis of potentials observed on the body surface potentials during a clinical procedure involving the infusion o...
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Article
The role of diagnostic laparoscopy in micropremmies with suspected necrotizing enterocolitis
The timely diagnosis of perforations or dead gut can be extremely difficult in micropremmies with necrotizing enterocolitis. A negative laparotomy is just as detrimental as failure to recognize early perforati...
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Article
Biological pacing by gene and cell therapy
At present, cardiac rhythm disorders such as sick sinus syndrome (SSS) or AV nodal block (AVB) are usually treated by electronic pacemakers. These devices have significant shortcomings, including lack of auton...
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Article
Gender disparities in torsade de pointes ventricular tachycardia
Background Gender disparities in the incidence of torsade de pointes (TdP) ventricular tachycardia exist, but the mechanisms in humans are unresolved. We addressed this issue using a mathematical model of a human...
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Chapter and Conference Paper
Local Filtered QRS Duration during Sodium-channel Blockade in Brugada Syndrome Patients
The Brugada syndrome is associated with sodium channel dysfunction and the characteristic ST segment elevation is thought to arise from the right ventricle. We hypothesized that sodium channel blockade in Brug...
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Article
Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death
At present, the signaling pathways controlling reactive nitrogen species (RNS)-induced non-apoptotic cell death are relatively less understood. In this work, various RNS donors are found to induce caspase-inde...