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Article
Open AccessAccuracy of mobile 6-lead electrocardiogram device for assessment of QT interval: a prospective validation study
Ambulatory assessment of the heart rate–corrected QT interval (QTc) can be of diagnostic value, for example in patients on QTc-prolonging medication. Repeating sequential 12-lead electrocardiograms (ECGs) to m...
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Article
Open AccessAutomated analysis of finger blood pressure recordings provides insight in determinants of baroreflex sensitivity and heart rate variability—the HELIUS study
Sympathovagal balance is important in the pathogenesis of hypertension and independently associated with mortality. We evaluated the value of automated analysis of cross-correlation baroreflex sensitivity (xBR...
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Article
Catheter ablation in highly symptomatic Brugada patients: a Dutch case series
In the past few years, promising results were described in targeting the arrhythmogenic substrate of the epicardial right ventricular outflow tract (RVOT) region in patients with Brugada syndrome (BrS). In thi...
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Article
Takotsubo cardiomyopathy shortly following pacemaker implantation—case report and review of the literature
We describe a patient with acute heart failure shortly after pacemaker implantation. With the documentation of typical dyskinesia of the apical segments with hyperdynamic contractility of the basal segments an...
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Article
A young man with near-syncope
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Article
A young man with near-syncope
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Article
Open AccessFounder mutations in the Netherlands: familial idiopathic ventricular fibrillation and DPP6
In this part of a series on founder mutations in the Netherlands, we review familial idiopathic ventricular fibrillation linked to the DPP6 gene. Familial idiopathic ventricular fibrillation determines an intrigu...
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Article
Open AccessRecurrent and Founder Mutations in the Netherlands: the Long-QT Syndrome
The long-QT syndrome (LQTS) is associated with premature sudden cardiac deaths affecting whole families and is caused by mutations in genes encoding for cardiac proteins. When the same mutation is found in dif...
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Article
Founder mutations in hypertrophic cardiomyopathy patients in the Netherlands
In this part of a series on cardiogenetic founder mutations in the Netherlands, we review the Dutch founder mutations in hypertrophic cardiomyopathy (HCM) patients.
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Article
Founder mutations in the Netherlands
In this part of a series on founder mutations in the Netherlands, we review a Dutch family carrying the SCN5a 1795insD mutation. We describe the advances in our understanding of the premature sudden cardiac death...
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Chapter and Conference Paper
Local Filtered QRS Duration during Sodium-channel Blockade in Brugada Syndrome Patients
The Brugada syndrome is associated with sodium channel dysfunction and the characteristic ST segment elevation is thought to arise from the right ventricle. We hypothesized that sodium channel blockade in Brug...
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Article
Clinical trial update I
The first Clinical Trial Update in Vienna was chaired by M. Simoons (Rotterdam, the Netherlands) and J. Marco (Monaco Cedex, Monaco). In this session, the latest follow-up data were presented on two subjects: ...