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Article
Lower thigh muscle mass is associated with all-cause and cardiovascular mortality in elderly hemodialysis patients
Higher body mass index appears protective in hemodialysis patients, although it remains to be determined which component of muscle or fat mass is primarily associated with this survival advantage.
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Chapter and Conference Paper
Modeling of Signal Transmissions in Nerves in Vitro for the Development of a Renal Nerve Cooling Device for Hypertension Control
Hyperactivity of the central nervous system may increase feedback gains in the hemodynamic system. We have been develo** a totally implantable renal nerve cooling system which is capable of changing the hype...
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Article
Validity of mid-arm muscular area measured by anthropometry in nonobese patients with increased muscle atrophy and variation of subcutaneous fat thickness
The anthropometric measurement of mid-arm muscular area (MAMA) involves overestimation because of various assumptions, this overestimation being progressive with increasing adiposity. However, the effects of m...
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Article
Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation
Mixed-lineage-leukemia (MLL) fusion oncogenes are closely involved in infant acute leukemia, which is frequently accompanied by mutations or overexpression of FMS-like receptor tyrosine kinase 3 (FLT3). Earlier s...
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Article
Identification of TSC-22 as a potential tumor suppressor that is upregulated by Flt3-D835V but not Flt3-ITD
Transforming growth factor-β (TGF-β)-stimulated clone-22 (TSC-22) was originally isolated as a TGF-β-inducible gene. In this study, we identified TSC-22 as a potential leukemia suppressor. Two types of FMS-like t...
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Article
ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
Expanded polyglutamine 72 repeat (polyQ72) aggregates induce endoplasmic reticulum (ER) stress-mediated cell death with caspase-12 activation and vesicular formation (autophagy). We examined this relationship ...
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Article
Beneficial action of candesartan cilexetil plus amlodipine or ACE inhibitors in chronic nondiabetic renal disease
Although multiple antihypertensive agents are required to control blood pressure (BP) in chronic renal disease, it remains undetermined whether the combination therapy with angiotensin receptor blockers (ARB) ...
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Article
Cloning of a gene encoding thermostable cellobiohydrolase from Thermoascus aurantiacus and its expression in yeast
A gene encoding a cellobiohydrolase (CBH) was isolated from Thermoascus aurantiacus IFO 9748 and designated as cbh1. The deduced amino acid sequence encoded by cbh1 showed high homology with the sequence of glyc...
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Article
Fabrication of single-mode waveguide structure in optical multimode fluoride fibers using self-channeled plasma filaments excited by a femtosecond laser
A permanent structure of a single-mode waveguide in optical multimode fluoride fibers was first fabricated using a self-channeled plasma filament excited by a femtosecond (110-fs) Ti:sapphire laser (λp=800 nm). T...
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Article
In situ observation of dynamics of plasma self-channeling and bulk modification in silica glasses induced by a high-intensity femtosecond laser
The time-resolved dynamics of plasma self-channeling and refractive index bulk modification in silica glasses were first observed in situ using a high-intensity femtosecond (110 fs) Ti:sapphire laser (λp=790 nm)....
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Article
An onion enzyme that makes the eyes water
A flavoursome, user-friendly bulb would give no cause for tears when chopped up.
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Article
Lipomatous primitive neuroectodermal tumor with a glioblastoma component: a case report
A case of extracerebellar lipomatous primitive neuroectodermal tumor (PNET) with glioblastoma multiforme (GBM) areas is reported. A 44-year-old woman who had been on antipsychotic agents for schizophrenia com...
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Chapter and Conference Paper
Synthesis and 57Fe and 151Eu Mössbauer Spectroscopic Studies of New Lanthanoid-iron Complexes
New lanthanoid-iron 2,2′-bipyridine (bpy) and 2,2′:6′,2″-terpyridine (terpy) complexes have been investigated by a variable temperature Mössbauer spectroscopy and a single crystal structure analysis. The cryst...
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Chapter
Chemo-enzymatic syntheses of eel calcitonin analogs having natural N-linked oligosaccharides
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Chapter
Chemo-enzymatic synthesis of bioactive peptide derivatives containing N-linked oligosaccharides
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Article
Brain perfusion measured by flow-sensitive alternating inversion recovery (FAIR) and dynamic susceptibility contrast-enhanced magnetic resonance imaging: comparison with nuclear medicine technique
The aim of this study was to compare cerebral perfusion images and regional cerebral blood flow (rCBF) of SPECT study with the images and regional intensity of relative cerebral blood flow (CBF) images acquir...
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Article
Two-dimensional thick-slice MR digital subtraction angiography for assessment of cerebrovascular occlusive diseases
Although spatial resolution of current MR angiography is excellent, temporal resolution has remained unsatisfactory. We evaluated clinical applicability of 2D thick-slice, contrast-enhanced subtraction MR ang...
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Article
Simultaneous display of MRA and MPR in detecting vascular compression for trigeminal neuralgia or hemifacial spasm: comparison with oblique sagittal views of MRI
A new technique, simultaneous display of magnetic resonance angiography (MRA) and multiplanar reconstruction (MPR), was performed by a workstation to identify the involved vessels in patients with trigeminal ...
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Article
High-yield production and characterization of α-galactosidase from Bifidobacterium breve grown on raffinose
Bifidobacteria assimilated raffinose about 4-fold more effectively than other intestinal bacteria, and α-galactosidase was active in all strains of Bifidobacteria tested. The enzyme activity of Bifidobacterium b...
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Article
Time-resolved two-dimensional thick-slice magnetic resonance digital subtraction angiography in assessing brain tumors
The aim of this study was to evaluate clinical applicability of two-dimensional (2D) thick-slice, contrast-enhanced magnetic resonance digital subtraction angiography (MRDSA) with high temporal resolution in ...
