10 Result(s)
within
H Takeshita
Cancer Research
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Article
Open AccessClinical impact of circulating miR-18a in plasma of patients with oesophageal squamous cell carcinoma
Several recent studies demonstrated that microRNAs are stably detectable in plasma/serum. We tested whether miR-18a, which is located in the miR-17-92 cluster and reported to be highly expressed in tissues of ...
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Article
Open AccessOverexpression of YWHAZ relates to tumor cell proliferation and malignant outcome of gastric carcinoma
Several studies have demonstrated that YWHAZ (14-3-3ζ), included in the 14-3-3 family of proteins, has been implicated in the initiation and progression of cancers. We tested whether YWHAZ acted as a cancer-promo...
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Article
Open AccessClinical impact of circulating miR-221 in plasma of patients with pancreatic cancer
Several recent studies have demonstrated that microRNAs (miRNAs) are stably detectable in plasma/serum. We tested miR-221 and miR-375, which are frequently reported to be highly and poorly expressed in pancrea...
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Article
Open AccessDetection of gastric cancer-associated microRNAs on microRNA microarray comparing pre- and post-operative plasma
Recently, it was reported that plasma microRNAs (miRNAs) are low-invasive useful biomarkers for cancer. We attempted to isolate gastric cancer (GC)-associated miRNAs comparing pre- and post-operative paired pl...
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Article
Open AccessNovel diagnostic value of circulating miR-18a in plasma of patients with pancreatic cancer
Several recent studies have demonstrated that microRNAs (miRNAs) are stably detectable in the plasma/serum. We hypothesised that miR-18a in the plasma is a potential biomarker in patients with pancreatic cancer.
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Article
Open AccessCirculating microRNAs in plasma of patients with oesophageal squamous cell carcinoma
Several recent studies demonstrated that microRNAs (miRNAs) are stably detectable in plasma/serum. We hypothesised that plasma miRNAs concentrations contributed to potential biomarkers in patients with oesopha...
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Article
Open AccessPrediction of CCND1 amplification using plasma DNA as a prognostic marker in oesophageal squamous cell carcinoma
We aimed to develop a new biomarker to predict cyclin D1 (CCND1) status using plasma DNA in oesophageal squamous cell carcinoma (ESCC) patients.
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Article
Open AccessCirculating microRNAs in plasma of patients with gastric cancers
We examined plasma microRNA (miRNA) concentrations from patients with gastric cancers (GCs) to assess their clinical application for diagnosing and monitoring diseases.
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Article
Open AccessCombined effects of a third-generation bisphosphonate, zoledronic acid with other anticancer agents against murine osteosarcoma
Bisphosphonates (BPs) are widely used to treat bone diseases and also appear to possess direct antitumour activity. We have previously reported that third-generation BPs such as zoledronic acid (ZOL) and minod...
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Article
Open AccessOsteoblastic differentiation and P-glycoprotein multidrug resistance in a murine osteosarcoma model
A recent study of multidrug resistance (MDR) 1 gene transfected osteosarcoma cells found a cause-effect relationship between increased expression of P-glycoprotein (P-gp) and a low aggressive phenotype. Howeve...
