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Open AccessIntrogression of pigs in Taihu Lake region possibly contributed to the improvement of fertility in Danish Large White pigs
Eurasian pigs have undergone lineage admixture throughout history. It has been confirmed that the genes of indigenous pig breeds in China have been introduced into Western commercial pigs, providing genetic ma...
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Open AccessComprehensive genomic analysis of the DUF4228 gene family in land plants and expression profiling of ATDUF4228 under abiotic stresses
Domain of unknown function (DUF) proteins represent a number of gene families that encode functionally uncharacterized proteins in eukaryotes. The DUF4228 gene family is one of these families in plants that has n...
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Open AccessUse of biological priors enhances understanding of genetic architecture and genomic prediction of complex traits within and between dairy cattle breeds
A better understanding of the genetic architecture underlying complex traits (e.g., the distribution of causal variants and their effects) may aid in the genomic prediction. Here, we hypothesized that the geno...
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Open AccessThe patterns of genomic variances and covariances across genome for milk production traits between Chinese and Nordic Holstein populations
With the development of SNP chips, SNP information provides an efficient approach to further disentangle different patterns of genomic variances and covariances across the genome for traits of interest. Due to...
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Open AccessDomestication of rice has reduced the occurrence of transposable elements within gene coding regions
Transposable elements (TEs) are prominent features in many plant genomes, and patterns of TEs in closely related rice species are thus proposed as an ideal model to study TEs roles in the context of plant geno...
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Open AccessGenome-wide association analyses using a Bayesian approach for litter size and piglet mortality in Danish Landrace and Yorkshire pigs
Litter size and piglet mortality are important traits in pig production. The study aimed to identify quantitative trait loci (QTL) for litter size and mortality traits, including total number of piglets born (...
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Open AccessGenome-wide association study in Chinese Holstein cows reveal two candidate genes for somatic cell score as an indicator for mastitis susceptibility
Bovine mastitis is a typical inflammatory disease causing seriously economic loss. Genome-wide association study (GWAS) can be a powerful method to promote marker assistant selection of this kind of complex di...
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Open AccessGenomic prediction of genetic merit using LD-based haplotypes in the Nordic Holstein population
A haplotype approach to genomic prediction using high density data in dairy cattle as an alternative to single-marker methods is presented. With the assumption that haplotypes are in stronger linkage disequili...
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Open AccessAccuracy of genomic prediction for growth and carcass traits in Chinese triple-yellow chickens
Growth and carcass traits are very important traits for broiler chickens. However, carcass traits can only be measured postmortem. Genomic selection may be a powerful tool for such traits because of its accura...
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Open AccessStrategies for imputation to whole genome sequence using a single or multi-breed reference population in cattle
The advent of low cost next generation sequencing has made it possible to sequence a large number of dairy and beef bulls which can be used as a reference for imputation of whole genome sequence data. The aim ...
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Open AccessAn integrated genomic and metabolomic framework for cell wall biology in rice
Plant cell walls are complex structures that full-fill many diverse functions during plant growth and development. It is therefore not surprising that thousands of gene products are involved in cell wall synth...
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Open AccessComparison of single-trait and multiple-trait genomic prediction models
In this study, a single-trait genomic model (STGM) is compared with a multiple-trait genomic model (MTGM) for genomic prediction using conventional estimated breeding values (EBVs) calculated using a conventio...
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Open AccessGenome wide association studies for body conformation traits in the Chinese Holstein cattle population
Genome-wide association study (GWAS) is a powerful tool for revealing the genetic basis of quantitative traits. However, studies using GWAS for conformation traits of cattle is comparatively less. This study a...
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Open AccessGenome position specific priors for genomic prediction
The accuracy of genomic prediction is highly dependent on the size of the reference population. For small populations, including information from other populations could improve this accuracy. The usual strate...
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Open AccessPartitioning additive genetic variance into genomic and remaining polygenic components for complex traits in dairy cattle
Low cost genoty** of individuals using high density genomic markers were recently introduced as genomic selection in genetic improvement programs in dairy cattle. Most implementations of genomic selection on...
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Open AccessEfficiency of genomic selection using Bayesian multi-marker models for traits selected to reflect a wide range of heritabilities and frequencies of detected quantitative traits loci in mice
Genomic selection uses dense single nucleotide polymorphisms (SNP) markers to predict breeding values, as compared to conventional evaluations which estimate polygenic effects based on phenotypic records and p...